Biomedical Sciences Research Complex (BSRC) Research: Recent submissions
Now showing items 6-10 of 28
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Organic light-emitting diodes for optogenetic stimulation of Drosophila larvae
(Optical Society of American (OSA), 2016-11-14) - Conference itemOptogenetics is an emerging method in biology that enables controlling neurons with light. We use organic light-emitting diodes to stimulate neurons in Drosophila larvae and investigate subsequent behavioral changes at ... -
A novel archaeal DNA repair factor that acts with the UvrABC system to repair mitomycin C-induced DNA damage in a PCNA-dependent manner
(2015-12-22) - Journal articleThe sliding clamp PCNA plays a vital role in a number of DNA repair pathways in eukaryotes and archaea by acting as a stable platform onto which other essential protein factors assemble. Many of these proteins interact ... -
Lipidomic analysis of fats and oils – a lot more than just omega-3
(2015-01) - Journal articleEdible oils and fats are among the most abundant cooking ingredients in the world, and are an important part of a healthy balanced diet, especially if they are high in omega-6 and omega-3 polyunsaturated fatty acids. Rather ... -
Taking a molecular motor for a spin : helicase mechanism studied by spin labelling and PELDOR
(2015-12-10) - Journal articleThe complex molecular motions central to the functions of helicases have long attracted attention. Protein crystallography has provided transformative insights into these dynamic conformational changes, however important ... -
Identification of a candidate Rad1 subunit for the kinetoplastid 9-1-1 (Rad9-Hus1-Rad1) complex
(2014-12-19) - Journal articleThe trimeric 9-1-1 (Rad9-Hus1-Rad1) complex plays an important role in the eukaryotic DNA damage response by recruiting DNA repair factors and checkpoint mediators to damaged sites. Extensively characterised in mammals and ...