Assessment of intradimensional/extradimensional attentional set-shifting in rats
MetadataShow full item record
The rat intradimensional/extradimensional (ID/ED) task, first described by Birrell and Brown 18 years ago, has become the predominant means by which attentional set-shifting is investigated in rodents: the use of rats in the task has been described in over 135 publications by researchers from nearly 90 universities and pharmaceutical companies. There is variation in the protocols used by different groups, including differences in apparatus, stimuli (both stimulus dimensions and exemplars within), and also the methodology. Nevertheless, most of these variations seem to be of little consequence: there is remarkable similarity in the profile of published data, with consistency of learning rates and in the size and reliability of the set-shifting and reversal ‘costs’. However, we suspect that there may be inconsistent data that is unpublished or perhaps ‘failed experiments’ that may have been caused by unintended deviations from effective protocols. The purpose of this review is to describe our approach and the rationale behind certain aspects of the protocol, including common pitfalls that are encountered when establishing an effective local protocol.
Tait , D S , Bowman , E M , Neuwirth , L S & Brown , V J 2018 , ' Assessment of intradimensional/extradimensional attentional set-shifting in rats ' , Neuroscience and Biobehavioral Reviews , vol. 89 , pp. 72-84 . https://doi.org/10.1016/j.neubiorev.2018.02.013
Neuroscience and Biobehavioral Reviews
© 2018 Elsevier Ltd. This work has been made available online in accordance with the publisher’s policies. This is the author created, accepted version manuscript following peer review and may differ slightly from the final published version. The final published version of this work is available at https://doi.org/10.1016/j.neubiorev.2018.02.013
DescriptionThe initial development of the attentional set-shifting task was supported by The Wellcome Trust (Project Grant 051945/Z/97/Z) and a Biotechnology and Biological Sciences Research Council (UK) Studentship to Jennifer M. Birrell.
Items in the St Andrews Research Repository are protected by copyright, with all rights reserved, unless otherwise indicated.