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Synthesis and stereochemical assignment of (+)-chamuvarinin
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dc.contributor.author | Florence, Gordon John | |
dc.contributor.author | Morris, Joanne Charleen | |
dc.contributor.author | Murray, Ross George | |
dc.contributor.author | Osler, Jonathan | |
dc.contributor.author | Vanga, Raghava Reddy | |
dc.contributor.author | Smith, Terry K | |
dc.date.accessioned | 2011-03-10T16:26:08Z | |
dc.date.available | 2011-03-10T16:26:08Z | |
dc.date.issued | 2011-02-04 | |
dc.identifier | 5052033 | |
dc.identifier | 8d348877-33dc-41b5-915c-5fa5833e5783 | |
dc.identifier | 000286577600042 | |
dc.identifier | 79851505529 | |
dc.identifier.citation | Florence , G J , Morris , J C , Murray , R G , Osler , J , Vanga , R R & Smith , T K 2011 , ' Synthesis and stereochemical assignment of (+)-chamuvarinin ' , Organic Letters , vol. 13 , no. 3 , pp. 514-517 . https://doi.org/10.1021/ol1028699 | en |
dc.identifier.issn | 1523-7060 | |
dc.identifier.other | ORCID: /0000-0001-9921-4399/work/56638879 | |
dc.identifier.uri | https://hdl.handle.net/10023/1685 | |
dc.description | Supported by grants from EPSRC (EP/F011458/1) and The Wellcome Trust (086658). | en |
dc.description.abstract | A stereocontrolled total synthesis of (+)-chamuvarinin, isolated from the root extract of Uvaria Chamae, utilizes a convergent modular strategy to construct the adjacently linked C15−C28 ether array, followed by a late-stage Julia−Kocienski olefination to append the butenolide motif. This constitutes the first total synthesis of (+)-chamuvarinin, defining the relative and absolute configuration of this unique annonaceous acetogenin. | |
dc.format.extent | 4 | |
dc.format.extent | 499471 | |
dc.language.iso | eng | |
dc.relation.ispartof | Organic Letters | en |
dc.subject | Hydrolytic kinetic resolution | en |
dc.subject | Annonaceous acetogenins | en |
dc.subject | Uvaria-chamae | en |
dc.subject | Stereoisomer library | en |
dc.subject | Recent progress | en |
dc.subject | Mosher method | en |
dc.subject | Bearing | en |
dc.subject | Condensation | en |
dc.subject | Mechanisms | en |
dc.subject | Murisolins | en |
dc.subject | QD Chemistry | en |
dc.subject.lcc | QD | en |
dc.title | Synthesis and stereochemical assignment of (+)-chamuvarinin | en |
dc.type | Journal article | en |
dc.contributor.sponsor | EPSRC | en |
dc.contributor.sponsor | The Wellcome Trust | en |
dc.contributor.sponsor | The Royal Society | en |
dc.contributor.institution | University of St Andrews. School of Chemistry | en |
dc.contributor.institution | University of St Andrews. Biomedical Sciences Research Complex | en |
dc.contributor.institution | University of St Andrews. School of Biology | en |
dc.contributor.institution | University of St Andrews. EaSTCHEM | en |
dc.identifier.doi | https://doi.org/10.1021/ol1028699 | |
dc.description.status | Peer reviewed | en |
dc.identifier.grantnumber | EP/F011458/1 | en |
dc.identifier.grantnumber | 086658 Z 08 Z | en |
dc.identifier.grantnumber | UF090005 | en |
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