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dc.contributor.authorSobota, Aleksandra
dc.contributor.authorOzakinci, Gozde
dc.identifier.citationSobota , A & Ozakinci , G 2018 , ' Determinants of fertility issues experienced by young women diagnosed with breast or gynaecological cancer - a quantitative, cross-cultural study ' , BMC Cancer , vol. 18 , no. 874 .
dc.identifier.otherPURE: 255427233
dc.identifier.otherPURE UUID: 03073f7f-d4fe-4e3e-bfa8-aba1a575e0fe
dc.identifier.otherScopus: 85052925688
dc.identifier.otherORCID: /0000-0001-5869-3274/work/48131982
dc.identifier.otherWOS: 000443892800002
dc.descriptionThis study was part of a PhD project funded by the Danuta Rischardson Medical Scholarship.en
dc.description.abstractBackground. Although there is a recognition of the importance of fertility to young women with cancer, we do not know who is at risk of distress related to fertility issues following diagnosis. We investigated the determinants of fertility-related distress adopting a cross-cultural perspective and using the Common Sense Model (CSM). We chose the CSM as a theoretical framework as it allows to explore how individuals conceptualise illness within the socio-cultural context. Methods. British and Polish women with breast or gynaecological cancer were recruited through outpatient clinics or online outlets and completed a questionnaire. Linear regression, mediation and moderated mediation methods were performed. Results. One hundred sixty-four women participated (mean age 34.55 (SD = 6.66); 78.7% had gynaecological cancer). The determinants of fertility-related distress were: country of origin, recruitment site, negative affect, desire to have children, treatment regret, and total illness perception score. The impact of the desire to have children on fertility-related distress was mediated by psychological value of children, perceived consequences of cancer on one’s life, emotional representation, and treatment-related regret. Country of origin moderated the relationship between the desire to have children and fertility-related distress when mediated by treatment-related regret. Conclusions. The CSM proved useful in investigating predictors of fertility-related distress, with emotional, rather than cognitive representation of illness determining its levels. Socio-cultural background played a role in determining one’s fertility-related distress and contributed to the explanation of the relationship between one’s desire to have children, treatment-related regret, and fertility-related distress.
dc.relation.ispartofBMC Canceren
dc.rights© The Author(s). 2018 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (, which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver ( applies to the data made available in this article, unless otherwise stated.en
dc.subjectAYA canceren
dc.subjectGynaecological canceren
dc.subjectBreast canceren
dc.subjectQuality of lifeen
dc.subjectR Medicine (General)en
dc.titleDeterminants of fertility issues experienced by young women diagnosed with breast or gynaecological cancer - a quantitative, cross-cultural studyen
dc.typeJournal articleen
dc.description.versionPublisher PDFen
dc.contributor.institutionUniversity of St Andrews.Population and Behavioural Science Divisionen
dc.contributor.institutionUniversity of St Andrews.Health Psychologyen
dc.contributor.institutionUniversity of St Andrews.St Andrews Sustainability Instituteen
dc.contributor.institutionUniversity of St Andrews.School of Medicineen
dc.description.statusPeer revieweden

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