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dc.contributor.authorSchibilla, Frauke
dc.contributor.authorHolthenrich, Anna
dc.contributor.authorSong, Boyi
dc.contributor.authorLinard Matos, Anna Lívia
dc.contributor.authorGrill, David
dc.contributor.authorRota Martir, Diego
dc.contributor.authorGerke, Volker
dc.contributor.authorZysman-Colman, Eli
dc.contributor.authorRavoo, Bart Jan
dc.date.accessioned2018-08-31T16:30:06Z
dc.date.available2018-08-31T16:30:06Z
dc.date.issued2018-10-28
dc.identifier.citationSchibilla , F , Holthenrich , A , Song , B , Linard Matos , A L , Grill , D , Rota Martir , D , Gerke , V , Zysman-Colman , E & Ravoo , B J 2018 , ' Phosphorescent cationic iridium(III) complexes dynamically bound to cyclodextrin vesicles : applications in live cell imaging ' Chemical Science , vol. 9 , no. 40 , pp. 7822-7828 . https://doi.org/10.1039/C8SC02875Cen
dc.identifier.issn2041-6520
dc.identifier.otherPURE: 255409195
dc.identifier.otherPURE UUID: 5b5e51a3-2399-4bff-9238-db32b8c1f292
dc.identifier.otherScopus: 85055494338
dc.identifier.otherScopus: 85055494338
dc.identifier.otherORCID: /0000-0001-7183-6022/work/56639111
dc.identifier.urihttp://hdl.handle.net/10023/15930
dc.descriptionThe authors are grateful for financial support by the Deutsche Forschungsgemeinschaft (DFG Ra 1732/7, SFB 858 and Ge 514/6) and Deutscher Akademischer Austauschdienst (DAAD). E.Z.-C. acknowledges the University of St. Andrews and EPSRC (EP/M02105X/1) for financial support.en
dc.description.abstractWe report cationic Ir(III) complexes functionalized with adamantyl groups designed to bind to β-cyclodextrin vesicles (CDV) with high affinity (Ka = 1·106 M-1). The emission of the complexes is tuned by changing the nature of the cyclometalating ligands. The host-guest adduct of CDV and Ir(III) complexes shows increased and significantly blue-shifted emission due to the lower mobility of the Ir(III)-complexes residing in the less polar environment of the vesicle surface. Ir(III)-decorated CDV are efficiently taken up by cells and can be used in live cell imaging. The CDV act as carriers to transport the phosphorescent complexes into cells where they selectively stain mitochondria.
dc.format.extent7
dc.language.isoeng
dc.relation.ispartofChemical Scienceen
dc.rightsCopyright 2018 the Authors. This Open Access article is licensed under a Creative Commons Attribution 3.0 Unported Licenceen
dc.subjectQD Chemistryen
dc.subjectDASen
dc.subject.lccQDen
dc.titlePhosphorescent cationic iridium(III) complexes dynamically bound to cyclodextrin vesicles : applications in live cell imagingen
dc.typeJournal articleen
dc.description.versionPostprinten
dc.description.versionPublisher PDFen
dc.contributor.institutionUniversity of St Andrews.Organic Semiconductor Centreen
dc.contributor.institutionUniversity of St Andrews.School of Chemistryen
dc.contributor.institutionUniversity of St Andrews.EaSTCHEMen
dc.identifier.doihttps://doi.org/10.1039/C8SC02875C
dc.description.statusPeer revieweden


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