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Inter and Intraspecific genomic divergence in Drosophila montana shows evidence for cold adaptation
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dc.contributor.author | Parker, Darren | |
dc.contributor.author | Wiberg, R. Axel W. | |
dc.contributor.author | Trivedi, Urmi | |
dc.contributor.author | Tyukmaeva, Venera I. | |
dc.contributor.author | Gharbi, Karim | |
dc.contributor.author | Butlin, Roger K. | |
dc.contributor.author | Hoikkala, Anneli | |
dc.contributor.author | Kankare, Maaria | |
dc.contributor.author | Ritchie, Michael | |
dc.date.accessioned | 2018-08-27T12:30:05Z | |
dc.date.available | 2018-08-27T12:30:05Z | |
dc.date.issued | 2018-08-01 | |
dc.identifier | 254611168 | |
dc.identifier | 47eeae64-17d9-4fe2-8b49-8164aa35f26d | |
dc.identifier | 000444553900020 | |
dc.identifier.citation | Parker , D , Wiberg , R A W , Trivedi , U , Tyukmaeva , V I , Gharbi , K , Butlin , R K , Hoikkala , A , Kankare , M & Ritchie , M 2018 , ' Inter and Intraspecific genomic divergence in Drosophila montana shows evidence for cold adaptation ' , Genome Biology and Evolution , vol. 10 , no. 8 , pp. 2086–2101 . https://doi.org/10.1093/gbe/evy147 | en |
dc.identifier.issn | 1759-6653 | |
dc.identifier.other | ORCID: /0000-0001-7913-8675/work/46761159 | |
dc.identifier.uri | https://hdl.handle.net/10023/15882 | |
dc.description | This work was supported by the Academy of Finland to AH (projects 132619 and 267244) and to MK (projects 268214 and 272927) and NERC (UK) funding to MGR (grants NE/E015255/1 and NE/J020818/1) and PhD studentship to DJP (NE/I528634/1). | en |
dc.description.abstract | The genomes of species that are ecological specialists will likely contain signatures of genomic adaptation to their niche. However, distinguishing genes related to ecological specialism from other sources of selection and more random changes is a challenge. Here we describe the genome of Drosophila montana, which is the most extremely cold-adapted Drosophila species. We use branch tests to identify genes showing accelerated divergence in contrasts between cold- and warm adapted species and identify about 250 genes that show differences, possibly driven by a lower synonymous substitution rate in cold-adapted species. We look for evidence of accelerated divergence between D. montana and D. virilis, a previously sequenced relative, and do not find strong evidence for divergent selection on coding sequence variation. Divergent genes are involved in a variety of functions, including cuticular and olfactory processes. We also re-sequenced three populations of D. montana from its ecological and geographic range. Outlier loci were more likely to be found on the X chromosome and there was a greater than expected overlap between population outliers and those genes implicated in cold adaptation between Drosophila species, implying some continuity of selective process at these different evolutionary scales. | |
dc.format.extent | 2087434 | |
dc.language.iso | eng | |
dc.relation.ispartof | Genome Biology and Evolution | en |
dc.subject | Cold tolerance | en |
dc.subject | Drosophilia montana | en |
dc.subject | Ecological adaptation | en |
dc.subject | Comparative genomics | en |
dc.subject | QH301 Biology | en |
dc.subject | DAS | en |
dc.subject.lcc | QH301 | en |
dc.title | Inter and Intraspecific genomic divergence in Drosophila montana shows evidence for cold adaptation | en |
dc.type | Journal article | en |
dc.contributor.sponsor | NERC | en |
dc.contributor.sponsor | NERC | en |
dc.contributor.institution | University of St Andrews. Centre for Biological Diversity | en |
dc.contributor.institution | University of St Andrews. Institute of Behavioural and Neural Sciences | en |
dc.contributor.institution | University of St Andrews. School of Biology | en |
dc.identifier.doi | https://doi.org/10.1093/gbe/evy147 | |
dc.description.status | Peer reviewed | en |
dc.identifier.grantnumber | NE/E015255/1 | en |
dc.identifier.grantnumber | NE/J020818/1 | en |
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