Show simple item record

Files in this item


Item metadata

dc.contributor.advisorReid, D. H.
dc.contributor.authorFraser, Martin
dc.coverage.spatial179 p.en_US
dc.description.abstractIndolizine was first synthesised by Scholts¹ in 1912 who proposed at that time the presently accepted ring structure (1). A number of alternative names and systems of numbering have been suggested for the heterocycle. These include pyrindole, pyrroline, pyrrosoline, 9 pyrrolopyridine and pyrrolo [1,2-a] pyridine. It is proposed to use the name indolozine and the numbering as shown in (1), in accordance with the recommendations of the I.U.P.A.C. Direct support for Scholts’ formulation of the structure of indolizine followed from its catalytic reduction² showing the presence of four double bonds, to a derivative identical with d-coniceine (a) (ostahydtoindolizine) which on degradation with ayanogen bromide yielded a1 condine (9-n-gropylpieridine). Further evidence substantiating this formulation of indolizine arises from consideration of numerous syntheses described below.en_US
dc.publisherUniversity of St Andrews
dc.titleIndolizines: with special reference to the action of electrophilic reagentsen_US
dc.contributor.sponsorDepartment of Scientific and Industrial Research (DSIR)en_US
dc.type.qualificationnamePhD Doctor of Philosophyen_US
dc.publisher.institutionThe University of St Andrewsen_US

This item appears in the following Collection(s)

Show simple item record