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dc.contributor.authorWoodford, Luke
dc.contributor.authorBianco, Giovanni
dc.contributor.authorIvanova, Yoana
dc.contributor.authorDale, Maeve
dc.contributor.authorElmer, Kathryn
dc.contributor.authorRae, Fiona
dc.contributor.authorLarcombe, Stephen D.
dc.contributor.authorHelm, Barbara
dc.contributor.authorFerguson, Heather M.
dc.contributor.authorBaldini, Francesco
dc.date.accessioned2018-03-27T10:30:05Z
dc.date.available2018-03-27T10:30:05Z
dc.date.issued2018-03-08
dc.identifier.citationWoodford , L , Bianco , G , Ivanova , Y , Dale , M , Elmer , K , Rae , F , Larcombe , S D , Helm , B , Ferguson , H M & Baldini , F 2018 , ' Vector species-specific association between natural Wolbachia infections and avian malaria in black fly populations ' , Scientific Reports , vol. 8 , 4188 . https://doi.org/10.1038/s41598-018-22550-zen
dc.identifier.issn2045-2322
dc.identifier.otherPURE: 252625091
dc.identifier.otherPURE UUID: 2f7d62ab-06b9-4804-aac5-29613137d9e8
dc.identifier.otherRIS: urn:AE4FDB379334AFB5960D68367E2BE4A8
dc.identifier.otherRIS: Woodford2018
dc.identifier.otherScopus: 85048250688
dc.identifier.otherORCID: /0000-0003-2530-2120/work/60427704
dc.identifier.otherWOS: 000426825900023
dc.identifier.urihttps://hdl.handle.net/10023/13025
dc.descriptionThanks to the Institute of Biodiversity Animal Health and Comparative Medicine (University of Glasgow) for funding vector traps.en
dc.description.abstractArtificial infection of mosquitoes with the endosymbiont bacteria Wolbachia can interfere with malaria parasite development. Therefore, the release of Wolbachia-infected mosquitoes has been proposed as a malaria control strategy. However, Wolbachia effects on vector competence are only partly understood, as indicated by inconsistent effects on malaria infection reported under laboratory conditions. Studies of naturally-occurring Wolbachia infections in wild vector populations could be useful to identify the ecological and evolutionary conditions under which these endosymbionts can block malaria transmission. Here we demonstrate the occurrence of natural Wolbachia infections in three species of black fly (genus Simulium), which is a main vector of the avian malaria parasite Leucocytozoon. Prevalence of Leucocytozoon was high (25%), but the nature and magnitude of its association with Wolbachia differed between black fly species. Wolbachia infection was positively associated with avian malaria infection in S. cryophilum, negatively associated in S. aureum, and unrelated in S. vernum. These differences suggest that Wolbachia interacts with the parasite in a vector host species-specific manner. This provides a useful model system for further study of how Wolbachia influences vector competence. Such knowledge, including the possibility of undesirable positive association, is required to guide endosymbiont based control methods.
dc.format.extent11
dc.language.isoeng
dc.relation.ispartofScientific Reportsen
dc.rights© The Author(s) 2018. Open Access. This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.en
dc.subjectQH301 Biologyen
dc.subjectDASen
dc.subjectSDG 3 - Good Health and Well-beingen
dc.subject.lccQH301en
dc.titleVector species-specific association between natural Wolbachia infections and avian malaria in black fly populationsen
dc.typeJournal articleen
dc.description.versionPublisher PDFen
dc.contributor.institutionUniversity of St Andrews. School of Biologyen
dc.identifier.doihttps://doi.org/10.1038/s41598-018-22550-z
dc.description.statusPeer revieweden


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