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Insulin-like growth factor binding proteins of teleost fishes
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dc.contributor.author | Garcia de la Serrana, Daniel | |
dc.contributor.author | Macqueen, Daniel J. | |
dc.date.accessioned | 2018-03-12T11:30:09Z | |
dc.date.available | 2018-03-12T11:30:09Z | |
dc.date.issued | 2018-03-12 | |
dc.identifier | 252416882 | |
dc.identifier | 1e71d0c5-7174-4226-a742-e8fe3442d0ce | |
dc.identifier | 85043485336 | |
dc.identifier | 000427156600002 | |
dc.identifier.citation | Garcia de la Serrana , D & Macqueen , D J 2018 , ' Insulin-like growth factor binding proteins of teleost fishes ' , Frontiers in Endocrinology , vol. 9 , 80 . https://doi.org/10.3389/fendo.2018.00080 | en |
dc.identifier.issn | 1664-2392 | |
dc.identifier.uri | https://hdl.handle.net/10023/12904 | |
dc.description | DGS would like to thank the Marine Alliance Science Technology Scotland (MASTS) for their support. MASTS is funded by the Scottish Funding Council (grant reference HR09011) and contributing institutions. | en |
dc.description.abstract | The insulin-like growth factor (IGF) binding protein (IGFBP) family has a broad range of physiological functions and a fascinating evolutionary history. This review focuses on the IGFBPs of teleost fishes, where genome duplication events have diversified gene repertoire, function and physiological regulation - with six core IGFBPs expanded into a family of over twenty genes in some lineages. In addition to briefly summarizing the current state of knowledge on teleost IGFBP evolution, function and expression-level regulation, we highlight gaps in our understanding, and promising areas for future work. | |
dc.format.extent | 12 | |
dc.format.extent | 1935177 | |
dc.language.iso | eng | |
dc.relation.ispartof | Frontiers in Endocrinology | en |
dc.subject | Insulin-like growth factor binding protein | en |
dc.subject | Teleost fish | en |
dc.subject | Genome duplication | en |
dc.subject | Physiology | en |
dc.subject | Comparative biology | en |
dc.subject | Gene family evolution | en |
dc.subject | QH301 Biology | en |
dc.subject | QH426 Genetics | en |
dc.subject.lcc | QH301 | en |
dc.subject.lcc | QH426 | en |
dc.title | Insulin-like growth factor binding proteins of teleost fishes | en |
dc.type | Journal item | en |
dc.contributor.institution | University of St Andrews. Marine Alliance for Science & Technology Scotland | en |
dc.contributor.institution | University of St Andrews. Scottish Oceans Institute | en |
dc.identifier.doi | 10.3389/fendo.2018.00080 | |
dc.description.status | Peer reviewed | en |
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