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Insulin-like growth factor binding proteins of teleost fishes

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dc.contributor.authorGarcia de la Serrana, Daniel
dc.contributor.authorMacqueen, Daniel J.
dc.date.accessioned2018-03-12T11:30:09Z
dc.date.available2018-03-12T11:30:09Z
dc.date.issued2018-03-12
dc.identifier.citationGarcia de la Serrana , D & Macqueen , D J 2018 , ' Insulin-like growth factor binding proteins of teleost fishes ' , Frontiers in Endocrinology , vol. 9 , 80 . https://doi.org/10.3389/fendo.2018.00080en
dc.identifier.issn1664-2392
dc.identifier.otherPURE: 252416882
dc.identifier.otherPURE UUID: 1e71d0c5-7174-4226-a742-e8fe3442d0ce
dc.identifier.otherScopus: 85043485336
dc.identifier.otherWOS: 000427156600002
dc.identifier.urihttps://hdl.handle.net/10023/12904
dc.descriptionDGS would like to thank the Marine Alliance Science Technology Scotland (MASTS) for their support. MASTS is funded by the Scottish Funding Council (grant reference HR09011) and contributing institutions.en
dc.description.abstractThe insulin-like growth factor (IGF) binding protein (IGFBP) family has a broad range of physiological functions and a fascinating evolutionary history. This review focuses on the IGFBPs of teleost fishes, where genome duplication events have diversified gene repertoire, function and physiological regulation - with six core IGFBPs expanded into a family of over twenty genes in some lineages. In addition to briefly summarizing the current state of knowledge on teleost IGFBP evolution, function and expression-level regulation, we highlight gaps in our understanding, and promising areas for future work.
dc.format.extent12
dc.language.isoeng
dc.relation.ispartofFrontiers in Endocrinologyen
dc.rights© 2018 Garcia de la Serrana and Macqueen. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.en
dc.subjectInsulin-like growth factor binding proteinen
dc.subjectTeleost fishen
dc.subjectGenome duplicationen
dc.subjectPhysiologyen
dc.subjectComparative biologyen
dc.subjectGene family evolutionen
dc.subjectQH301 Biologyen
dc.subjectQH426 Geneticsen
dc.subject.lccQH301en
dc.subject.lccQH426en
dc.titleInsulin-like growth factor binding proteins of teleost fishesen
dc.typeJournal itemen
dc.description.versionPublisher PDFen
dc.contributor.institutionUniversity of St Andrews. Marine Alliance for Science & Technology Scotlanden
dc.contributor.institutionUniversity of St Andrews. Scottish Oceans Instituteen
dc.identifier.doihttps://doi.org/10.3389/fendo.2018.00080
dc.description.statusPeer revieweden


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