Show simple item record

Files in this item


Item metadata

dc.contributor.authorAnderson, Amanda E.
dc.contributor.authorBaddeley, Christopher J.
dc.contributor.authorWright, Paul A.
dc.identifier.citationAnderson , A E , Baddeley , C J & Wright , P A 2017 , ' Tuning Pd-nanoparticle@MIL-101(Cr) catalysts for tandem reductive amination ' , Catalysis Letters , vol. In press .
dc.identifier.otherPURE: 251447280
dc.identifier.otherPURE UUID: 7e33ce4d-b71c-4d21-a3bc-5e729a57ddc9
dc.identifier.otherScopus: 85035134902
dc.identifier.otherORCID: /0000-0001-9750-6494/work/57330774
dc.identifier.otherORCID: /0000-0002-4243-9957/work/62668254
dc.identifier.otherWOS: 000419901300017
dc.descriptionThe authors thank the EPSRC (EP/L505079/1), SASOL Technology UK and the University of St Andrews for funding.en
dc.description.abstractThe versatility of MOFs as highly porous Lewis acidic supports for precious metal nanoparticles has been exploited for one-pot tandem reductive amination catalysis. MIL-101(Cr) loaded with Pd nanoparticles ca. 3 nm in size at 0.2–1 wt% has been used to catalyse the reaction of 4′-fluoroacetophenone with benzylamine under 10 bar of H2 to give the secondary amine, 4′-fluoro-α-methyl-N-phenylmethylbenzenemethanamine. For the highest Pd loading, major hydrogenolysis of the secondary amine occurs in a second tandem reaction, but by changing the ratio of Pd to Lewis acidic Cr3+ active sites it is possible to tune the catalytic selectivity to the desired 2° amine product. An empirical kinetic analysis was performed to demonstrate this active site complementarity.
dc.relation.ispartofCatalysis Lettersen
dc.rights© The Author(s) 2017. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (, which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.en
dc.subjectTandem reductive aminationen
dc.subjectKinetic modellingen
dc.subjectQD Chemistryen
dc.titleTuning Pd-nanoparticle@MIL-101(Cr) catalysts for tandem reductive aminationen
dc.typeJournal articleen
dc.description.versionPublisher PDFen
dc.contributor.institutionUniversity of St Andrews. School of Chemistryen
dc.contributor.institutionUniversity of St Andrews. EaSTCHEMen
dc.description.statusPeer revieweden

This item appears in the following Collection(s)

Show simple item record