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dc.contributor.authorCammen, Kristina
dc.contributor.authorAndrews, Kimberley
dc.contributor.authorCarroll, Emma Louise
dc.contributor.authorFoote, Andrew
dc.contributor.authorHumble, Emily
dc.contributor.authorKhudyakov, Jane
dc.contributor.authorLouis, Marie
dc.contributor.authorMcGowen, Michael
dc.contributor.authorOlsen, Morten
dc.contributor.authorVan Cise, Amy
dc.identifier.citationCammen , K , Andrews , K , Carroll , E L , Foote , A , Humble , E , Khudyakov , J , Louis , M , McGowen , M , Olsen , M & Van Cise , A 2016 , ' Genomic methods take the plunge : recent advances in high-throughput sequencing of marine mammals ' Journal of Heredity , vol. 107 , no. 6 , pp. 481-495 .
dc.identifier.otherPURE: 244378433
dc.identifier.otherPURE UUID: 0c95bd16-539f-4858-86f5-56669ab23fd2
dc.identifier.otherScopus: 84992016870
dc.description.abstractThe dramatic increase in the application of genomic techniques to non-model organisms (NMOs) over the past decade has yielded numerous valuable contributions to evolutionary biology and ecology, many of which would not have been possible with traditional genetic markers. We review this recent progression with a particular focus on genomic studies of marine mammals, a group of taxa that represent key macroevolutionary transitions from terrestrial to marine environments and for which available genomic resources have recently undergone notable rapid growth. Genomic studies of NMOs utilize an expanding range of approaches, including whole genome sequencing, restriction site-associated DNA sequencing, array-based sequencing of single nucleotide polymorphisms and target sequence probes (e.g., exomes), and transcriptome sequencing. These approaches generate different types and quantities of data, and many can be applied with limited or no prior genomic resources, thus overcoming one traditional limitation of research on NMOs. Within marine mammals, such studies have thus far yielded significant contributions to the fields of phylogenomics and comparative genomics, as well as enabled investigations of fitness, demography, and population structure. Here we review the primary options for generating genomic data, introduce several emerging techniques, and discuss the suitability of each approach for different applications in the study of NMOs.en
dc.relation.ispartofJournal of Heredityen
dc.rights© 2016, The American Genetics Association. This work is made available online in accordance with the publisher’s policies. This is the author created, accepted version manuscript following peer review and may differ slightly from the final published version. The final published version of this work is available at /
dc.subjectNon-model organismsen
dc.subjectSNP arrayen
dc.subjectTarget sequence captureen
dc.subjectWhole genome sequencingen
dc.subjectQH426 Geneticsen
dc.subjectQL Zoologyen
dc.titleGenomic methods take the plunge : recent advances in high-throughput sequencing of marine mammalsen
dc.typeJournal itemen
dc.contributor.institutionUniversity of St Andrews. School of Biologyen
dc.contributor.institutionUniversity of St Andrews. Sea Mammal Research Uniten
dc.description.statusPeer revieweden

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