Heterogeneous hydrogenation of esters under mild conditions using solid-supported phosphorus-ruthenium catalysts
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The catalytic reduction of esters using H2 offers a more sustainable alternative compared to classic stoichiometric reagents. Nowadays a wide range of highly efficient homogeneous catalysts are known, but these suffer from poor catalyst recoverability. Therefore, most industrial applications are based on heterogeneous catalysts but these processes are generally operated under harsh conditions (>200 °C, >100 bar). Here we describe the first catalytic system which combines the activity of homogeneous catalysts with the recoverability of a heterogeneous catalyst. The presented system is capable of hydrogenating esters under very mild conditions (25 °C, 50 bar) and could easily be recovered. The catalyst is based on phosphorus ligands covalently attached to a polymeric support and could be readily obtained via a facile solid-phase synthetic protocol in high yields with minimal workup.
Heutz , F J L , Erken , C , Aguila , M J B , Lefort , L & Kamer , P C J 2016 , ' Heterogeneous hydrogenation of esters under mild conditions using solid-supported phosphorus-ruthenium catalysts ' ChemCatChem , vol 8 , no. 11 , pp. 1896–1900 . DOI: 10.1002/cctc.201600330
© 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. This work is made available online in accordance with the publisher’s policies. This is the author created, accepted version manuscript following peer review and may differ slightly from the final published version. The final published version of this work is available at https://dx.doi.org/10.1002/cctc.201600330
The authors thank the European Union (Marie Curie ITN SusPhos, Grant Agreement No. 317404) for financial support.
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