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The relationship between cancer patient's fear of recurrence and chemotherapy : a systematic review and meta-analysis
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dc.contributor.author | Yang, Yuan | |
dc.contributor.author | Wen, Yunhong | |
dc.contributor.author | Bedi, Carolyn | |
dc.contributor.author | Humphris, Gerry | |
dc.date.accessioned | 2017-05-17T16:30:13Z | |
dc.date.available | 2017-05-17T16:30:13Z | |
dc.date.issued | 2017-07 | |
dc.identifier | 249930915 | |
dc.identifier | 7bd9d975-517e-4e0e-bf10-79e5273201bf | |
dc.identifier | 85018881729 | |
dc.identifier | 000403735100008 | |
dc.identifier.citation | Yang , Y , Wen , Y , Bedi , C & Humphris , G 2017 , ' The relationship between cancer patient's fear of recurrence and chemotherapy : a systematic review and meta-analysis ' , Journal of Psychosomatic Research , vol. 98 , pp. 55-63 . https://doi.org/10.1016/j.jpsychores.2017.05.002 | en |
dc.identifier.issn | 0022-3999 | |
dc.identifier.other | RIS: urn:ADC6E3C3C30AADA786078C7A948F6E85 | |
dc.identifier.uri | https://hdl.handle.net/10023/10791 | |
dc.description | This review was funded by Breast Cancer Now (grant number 6873). | en |
dc.description.abstract | Objective: The study aim was to provide an overview of the current evidence available on the link between chemotherapy (CTX) and fear of cancer recurrence (FoR). Methods: PubMED, Medline, Embase, PsycINFO and Web of Science databases were searched to identify relevant studies. Two authors independently selected and assessed the studies regarding eligibility criteria. Meta-analysis of suitable studies was conducted, and quality rated. Results: Forty eligible studies were included in the systematic review and twenty-nine of them were included in further meta-analysis. Meta-analysis of the available data confirmed a weak relationship between CTX and FoR (29 studies, 30,176 patients, overall r = 0.093, 95%, CI: 0.062–0.123, P < 0.001). Conclusions: The meta-analysis demonstrates a weak but significant relationship between cancer patient's FoR and the receipt of chemotherapy. However, these results should be interpreted with caution. Further investigation is warranted to explore possible mechanisms of FoR increase in patients who receive chemotherapy. Longitudinal studies assessing the trajectory of FoR during chemotherapy are also warranted. | |
dc.format.extent | 9 | |
dc.format.extent | 499710 | |
dc.language.iso | eng | |
dc.relation.ispartof | Journal of Psychosomatic Research | en |
dc.subject | Chemotherapy | en |
dc.subject | Cancer | en |
dc.subject | Fear of recurrence | en |
dc.subject | Meta-analysis | en |
dc.subject | Oncology | en |
dc.subject | Systematic review | en |
dc.subject | RA0421 Public health. Hygiene. Preventive Medicine | en |
dc.subject | RC0254 Neoplasms. Tumors. Oncology (including Cancer) | en |
dc.subject | BF Psychology | en |
dc.subject | RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry | en |
dc.subject | SDG 3 - Good Health and Well-being | en |
dc.subject.lcc | RA0421 | en |
dc.subject.lcc | RC0254 | en |
dc.subject.lcc | BF | en |
dc.subject.lcc | RC0321 | en |
dc.title | The relationship between cancer patient's fear of recurrence and chemotherapy : a systematic review and meta-analysis | en |
dc.type | Journal item | en |
dc.contributor.institution | University of St Andrews. School of Medicine | en |
dc.contributor.institution | University of St Andrews. WHO Collaborating Centre for International Child & Adolescent Health Policy | en |
dc.contributor.institution | University of St Andrews. Health Psychology | en |
dc.contributor.institution | University of St Andrews. St Andrews Sustainability Institute | en |
dc.identifier.doi | 10.1016/j.jpsychores.2017.05.002 | |
dc.description.status | Peer reviewed | en |
dc.identifier.url | http://www.sciencedirect.com/science/article/pii/S0022399917302192#appd001 | en |
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