Now showing items 56-60 of 155

    • A role for mitsugumin 23 in cardiac sarcoplasmic reticulum calcium leak 

      Robertson, Gavin B. (University of St Andrews, 2019-06-28) - Thesis
      Carefully controlled intracellular Ca²⁺-release is essential for maintenance of normal cardiac function. In failing hearts, dysregulated Zn²⁺-homeostasis is associated with disrupted intracellular Ca²⁺-homeostasis, however ...
    • All-optical assay to study biological neural networks 

      Afshar Saber, Wardiya (University of St Andrews, 2019-06-28) - Thesis
      As life span increases, neurodegenerative diseases such as dementia, Parkinson’s disease, Huntington’s disease, amyotrophic lateral sclerosis become an emerging problem in modern society. In particular Alzheimer’s ...
    • Computational image analysis in clear cell renal cell carcinoma 

      Um, In Hwa (University of St Andrews, 2019-12-03) - Thesis
      Background: In the UK, kidney cancer is the most lethal urologic cancer whose major subtype is renal cell carcinoma (RCC). Surgical resection is the first line of the treatment for renal cell carcinoma (RCC). A number ...
    • The neighbourhood social environment and its role in adolescent alcohol use and drinking motives 

      Martin, Gina Chrissy (University of St Andrews, 2019-06-28) - Thesis
      In Scotland, adolescent alcohol consumption represents a major public health concern. The overarching aim of this research was to identify neighbourhood characteristics associated with adolescent alcohol use behaviours ...
    • Influence of plasma fatty acids on serum albumin-metal interactions and blood clotting 

      Katundu, Kondwani George Happy (University of St Andrews, 2019-12-03) - Thesis
      Non-communicable diseases (NCDs) are a cause of high mortality and morbidity globally. HIV infection has complicated the burden of NCDs further by increasing its prevalence, mostly in lowand middle-income countries. NCDs ...