Medicine: Recent submissions
Now showing items 86-90 of 218
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Crambled : a Shiny application to enable intuitive resolution of conflicting cellularity estimates
(2015-12-07) - Journal articleIt is now commonplace to investigate tumour samples using whole-genome sequencing, and some commonly performed tasks are the estimation of cellularity (or sample purity), the genome-wide profiling of copy numbers, and the ... -
Experimental models of cryptococcosis
(2012) - Journal itemCryptococcosis is a life-threatening fungal disease that infects around one million people each year. Establishment and progression of disease involves a complex interplay between the fungus and a diverse range of host ... -
Investigating the role of Zn²⁺ in regulating the function of intracellular Ca²⁺-release channels
(University of St Andrews, 2018-12-06) - ThesisThe tightly regulated openings of the cardiac ryanodine receptor (RyR2) help to ensure that intracellular Ca²⁺- release from the sarcoplasmic reticulum (SR) can only occur when heart contractions are required. Usually ... -
Somatic cancer genetics in the UK : real-world data from phase I of the Cancer Research UK Stratified Medicine Programme
(2018-09-05) - Journal articleIntroduction: Phase I of the Cancer Research UK Stratified Medicine Programme (SMP1) was designed to roll out molecular pathology testing nationwide at the point of cancer diagnosis, as well as facilitate an infrastructure ... -
Has primary care antimicrobial use really been increasing? Comparison of changes in different prescribing measures for a complete geographic population 1995–2014
(2017-10-01) - Journal articleObjectives To elucidate how population trends in total antimicrobials dispensed in the community translate into individual exposure. Methods Retrospective, population-based observational study of all antimicrobial prescribing ...