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dc.contributor.advisorDholakia, Kishan
dc.contributor.authorRudhall, Andrew Peter
dc.description.abstractBroadband spectral content is required to support ultrashort pulses. However this broadband content is subject to dispersion and hence the pulse duration of corresponding ultrashort pulses may be stretched accordingly. I used a commercially-available adaptive ultrashort pulse shaper featuring multiphoton intrapulse interference phase scan technology to characterise and compensate for the dispersion of the optical system in situ and conducted experimental and theoretical studies in various inter-linked topics relating to the light-matter interaction. Firstly, I examined the role of broadband ultrashort pulses in novel light-matter interacting systems involving optically co-trapped particle systems in which inter-particle light scattering occurs between optically-bound particles. Secondly, I delivered dispersion-compensated broadband ultrashort pulses in a dispersive microscope system to investigate the role of pulse duration in a biological light-matter interaction involving laser-induced cell membrane permeabilisation through linear and nonlinear optical absorption. Finally, I examined some of the propagation characteristics of broadband ultrashort pulse propagation using a computer-controlled spatial light modulator. The propagation characteristics of ultrashort pulses is of paramount importance for defining the light-matter interaction in systems. The ability to control ultrashort pulse propagation by using adaptive dispersion compensation enables chirp-free ultrashort pulses to be used in experiments requiring the shortest possible pulses for a specified spectral bandwidth. Ultrashort pulsed beams may be configured to provide high peak intensities over long propagation lengths, for example, using novel beam shapes such as Bessel-type beams, which has applications in biological light-matter interactions including phototransfection based on laser-induced cell membrane permeabilisation. The need for precise positioning of the beam focus on the cell membrane becomes less strenuous by virtue of the spatial properties of the Bessel beam. Dispersion compensation can be used to control the temporal properties of ultrashort pulses thus permitting, for example, a high peak intensity to be maintained along the length of a Bessel beam, thereby reducing the pulse energy required to permeabilise the cell membrane and potentially reduce damage therein.en_US
dc.publisherUniversity of St Andrews
dc.rightsCreative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported
dc.subjectPulse shapingen_US
dc.subjectNonlinear opticsen_US
dc.subjectSecond harmonic generationen_US
dc.subjectOptical tweezingen_US
dc.subjectOptical bindingen_US
dc.subjectBessel beamen_US
dc.subjectBeam shapingen_US
dc.subjectUltrashort pulsesen_US
dc.subjectNovel beam shapesen_US
dc.subjectChromatic dispersionen_US
dc.subjectTemporal dispersionen_US
dc.subjectSpatial dispersionen_US
dc.subjectSpatial distortionen_US
dc.subjectSpatio-temporal pulse shapingen_US
dc.subjectNonlinear absorptionen_US
dc.subjectMultiphoton absorptionen_US
dc.subjectDispersion compensationen_US
dc.subjectSpatial light modulatoren_US
dc.subjectFrequency domainen_US
dc.subjectTime domainen_US
dc.subjectSpatial domainen_US
dc.subjectBroadband ultrashort pulsesen_US
dc.subjectBeam characterisationen_US
dc.subjectLight-matter interactionen_US
dc.subjectLinear absorptionen_US
dc.subjectMultiphoton intrapulse interferenceen_US
dc.subjectMultiphoton intrapulse interference phase scanen_US
dc.subjectPulse durationen_US
dc.subjectTime-bandwidth producten_US
dc.subjectCell membraneen_US
dc.subjectChirp compensationen_US
dc.subjectAdaptive pulse shaperen_US
dc.subject.lcshLaser pulses, Ultrashorten_US
dc.titleUltrashort laser pulse shaping for novel light fields and experimental biophysicsen_US
dc.type.qualificationnamePhD Doctor of Philosophyen_US
dc.publisher.institutionThe University of St Andrewsen_US

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Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported
Except where otherwise noted within the work, this item's licence for re-use is described as Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported