Biology
The School promotes an interdisciplinary approach to both applied and fundamental research problems and to postgraduate training. Research in the School is organised into three major interdisciplinary centres: the Scottish Oceans Institute (SOI), Biomedical Sciences Research Complex (BSRC) and Centre for Biological Diversity (CBD). Together these centres encompass the full spectrum of research in biological sciences, spanning investigations on the properties and behaviour of individual molecules to planetary environmental dynamics.
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Molecular mechanisms and functional consequences of chromatin binding by the human cytomegalovirus proteins IE1 and pUL83
(University of St Andrews, 2022-06-15) - ThesisInterferons (IFN) are an essential component of the vertebrate innate immune system against viruses and other pathogens. Human Cytomegalovirus (HCMV), like other viruses, has developed strategies to evade the host IFN ... -
Social plasticity within and across generations : testing the role of plasticity in rapid evolution in field cricket Teleogryllus oceanicus
(2021-06-30) - ThesisThe field of evolutionary biology lacks a full understanding of how phenotypic plasticity influences adaptive evolution, despite over a century of research effort. One under-studied question within this topic is whether ... -
An experimental investigation of the evolutionary dynamics of phenotypic plasticity under relaxed selection in threespine sticklebacks (Gasterosteus aculeatus)
(University of St Andrews, 2022-06-27) - ThesisHere I provide an overview of the ways in which phenotypic plasticity is suggested to be relevant to evolutionary dynamics, and examine the various predicted dynamics of plastic traits in novel environments. Following on ... -
Structure and mechanism of two type III CRISPR defence nucleases activated by cyclic oligoadenylate
(2022-06-15) - ThesisProkaryotes have a wide range of antiviral strategies to defend against invading mobile genetic elements (MGEs). Type III CRISPR-Cas systems typically synthesise cyclic oligoadenylate (cOA) second messengers upon binding ... -
Exploring mixed-species grouping effects through antipredator mechanisms
(University of St Andrews, 2022-06-15) - ThesisPredation is an important selective force for prey organisms, which have also developed different antipredator adaptions. Individuals of many animal species live in the group, which is generally believed to offer prey ...
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