Medicine (School of): Recent submissions
Now showing items 61-65 of 218
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The neighbourhood social environment and its role in adolescent alcohol use and drinking motives
(University of St Andrews, 2019-06-28) - ThesisIn Scotland, adolescent alcohol consumption represents a major public health concern. The overarching aim of this research was to identify neighbourhood characteristics associated with adolescent alcohol use behaviours ... -
Influence of plasma fatty acids on serum albumin-metal interactions and blood clotting
(University of St Andrews, 2019-12-03) - ThesisNon-communicable diseases (NCDs) are a cause of high mortality and morbidity globally. HIV infection has complicated the burden of NCDs further by increasing its prevalence, mostly in lowand middle-income countries. NCDs ... -
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(University of St Andrews, 2019-06-28) - Thesis -
Exploring additional mechanisms of cell injury by fluoropyrimidines in the treatment of cancer: an investigation of novel protide NUC-3373
(University of St Andrews, 2019-06-28) - Thesis5-Fluorouracil (5-FU) has been the backbone of chemotherapy for solid tumours such as colorectal cancer (CRC) for over 60 years. Despite advances in combinatorial treatments, most patients experience innate or acquired ... -
Exploration of the pharmacodynamic profile of Acelarin, a novel ProTide drug, in an in vitro model of ovarian cancer
(University of St Andrews, 2019-06-28) - ThesisAlthough most women with ovarian cancer initially respond to platinum-based therapy, overall survival is poor with only 45% of women alive 5 years after diagnosis. Gemcitabine, a fluoropyrimidine analogue often used when ...