Medicine (School of): Recent submissions
Now showing items 1-5 of 218
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Investigating the impact of the management of subclinical hypothyroidism on long-term clinical outcomes
(2025-07-04) - ThesisAbstract redacted -
Predicting recruitment to randomised controlled trials in general practice with machine learning through an Early Lung Cancer Detection Study
(2024-12-03) - ThesisAbstract redacted -
The NFE2L1 transcription factor is a key modulator of the stress response in podocytes
(2022-06-17) - ThesisBackground: Chronic kidney disease (CKD) is a major public health problem, particularly in the elderly. Injury to any part of the nephron cause kidney failure. However, glomerular damage, caused by primary glomerular ... -
Investigating resistance mechanisms to CB-839 in renal cell carcinoma using a whole-genome CRISPR/Cas9 approach
(2021-11-30) - ThesisRenal cell carcinoma (RCC) represents around 3% of all malignancies worldwide, with its most common type, clear cell RCC (ccRCC), making up around 70-80% of all RCC. RCC is characterised by significant tumour heterogeneity ... -
Developing a novel molecular bacterial load assay to improve clinical management of Mycobacterium abscessus infections
(2022-06-17) - ThesisMycobacterium abscessus (M. abscessus) is one of the most common rapid growing non- tuberculous mycobacteria (NTM) causing pulmonary disease (PD). Treatment involves long and toxic multi-drug regimens with uncertain benefit. ...