Browsing by Name "Houlston, Richard S"

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Genetic risk scores may compound rather than solve the issue of prostate cancer overdiagnosis

Horton, Rachel H; Dunlop, Malcolm G; Houlston, Richard S; Lucassen, Anneke; McCartney, Margaret; McNeill, Alan; Sud, Amit (2022-11-28) - Journal item
Utility of polygenic risk scores in UK cancer screening : a modelling analysis

Huntley, Catherine; Torr, Bethany; Sud, Amit; Rowlands, Charlie F; Way, Rosalind; Snape, Katie; Hanson, Helen; Swanton, Charles; Broggio, John; Lucassen, Anneke; McCartney, Margaret; Houlston, Richard S; Hingorani, Aroon D; Jones, Michael E; Turnbull, Clare (2023-06-01) - Journal article

Background It is proposed that, through restriction to individuals delineated as high risk, polygenic risk scores (PRSs) might enable more efficient targeting of existing cancer screening programmes and enable extension ...