Now showing items 1-2 of 2
Crambled : a Shiny application to enable intuitive resolution of conflicting cellularity estimates
(2015-12-07) - Journal article
It is now commonplace to investigate tumour samples using whole-genome sequencing, and some commonly performed tasks are the estimation of cellularity (or sample purity), the genome-wide profiling of copy numbers, and the ...
Mobile element insertions are frequent in oesophageal adenocarcinomas and can mislead paired-end sequencing analysis
(2015-07-10) - Journal article
Background: Mobile elements are active in the human genome, both in the germline and cancers, where they can mutate driver genes. Results: While analysing whole genome paired-end sequencing of oesophageal adenocarcinomas ...