Now showing items 1-10 of 14
Inferring transcriptional logic from multiple dynamic experiments
(2017-11-01) - Journal article
Motivation: The availability of more data of dynamic gene expression under multiple experimental conditions provides new information that makes the key goal of identifying not only the transcriptional regulators of a gene ...
Correlation estimation using components of Japanese candlesticks
(2016) - Journal article
Using the wick's difference from the classical Japanese candlestick representation of daily open, high, low, close prices brings efficiency when estimating the correlation in a bivariate Brownian motion. An interpretation ...
A unified framework for modelling wildlife population dynamics
(2005) - Journal article
This paper proposes a unified framework for defining and fitting stochastic, discrete-time, discrete-stage population dynamics models. The biological system is described by a state–space model, where the true but unknown ...
Retrospective power analysis
(1997) - Journal article
Many papers have appeared in the recent biological literature encouraging us to incorporate statistical power analysis into our hypothesis testing protocol (Peterman 1990; Fairweather 1991; Muller & Benignus 1992; Taylor ...
Decomposition tables for experiments. II. Two–one randomizations
(2010-10) - Journal article
We investigate structure for pairs of randomizations that do not follow each other in a chain. These are unrandomized-inclusive, independent, coincident or double randomizations. This involves taking several structures ...
Adaptive multivariate global testing
(2014-06) - Journal article
We present a methodology for dealing with recent challenges in testing global hypotheses using multivariate observations. The proposed tests target situations, often arising in emerging applications of neuroimaging, where ...
Distance software: design and analysis of distance sampling surveys for estimating population size
(2010) - Journal article
1. Distance sampling is a widely used technique for estimating the size or density of biological populations. Many distance sampling designs and most analyses use the software Distance. 2. We briefly review distance sampling ...
Inference from randomized (factorial) experiments
(2017) - Journal article
This is a contribution to the discussion of the interesting paper by Ding [Statist. Sci. 32 (2017) 331–345], which contrasts approaches attributed to Neyman and Fisher. I believe that Fisher’s usual assumption was ...
Nested row-column designs for near-factorial experiments with two treatment factors and one control treatment
(2015-10) - Journal article
This paper presents some methods of designing experiments in a block design with nested rows and columns. The treatments consist of all combinations of levels of two treatment factors, with an additional control treatment.
Statistical issues in first-in-human studies on BIA 10-2474: neglected comparison of protocol against practice
(2017-03-15) - Journal article
By setting the regulatory-approved protocol for a suite of first-in-human studies on BIA 10-2474 against the subsequent French investigations, we highlight six key design and statistical issues which reinforce recommendations ...