Now showing items 1-10 of 12
The Hox-TALE has been wagging for a long time
(2014-03-18) - Journal item
Hox and TALE proteins interact in a sea anemone, just as they do in flies and mice, indicating that the Hox-TALE system originated very early in animal evolution.
Evolution of signal multiplexing by 14-3-3-binding 2R-ohnologue protein families in the vertebrates
(2012-07) - Journal article
14-3-3 proteins regulate cellular responses to stimuli by docking onto pairs of phosphorylated residues on target proteins. The present study shows that the human 14-3-3-binding phosphoproteome is highly enriched in ...
The dynamics of alkaline phosphatase activity during operculum regeneration in the polychaete Pomatoceros lamarckii
(2014) - Journal article
Alkaline phosphatase enzymes are found throughout the living world and fulfil a variety of functions. They have been linked to regeneration, stem cells and biomineralisation in a range of animals. Here we describe the ...
Biomineralisation during operculum regeneration in the polychaete Spirobranchus lamarcki
(2014-11) - Journal article
Formation of calcified biominerals is widespread in marine animals and is often associated with important elements of their biology, such as support and protection. Serpulid polychaetes are relatively understudied examples ...
Cell proliferation dynamics in regeneration of the operculum head appendage in the annelid Pomatoceros lamarckii
(2014-07) - Journal article
Regeneration of lost or damaged appendages is a widespread and ecologically important ability in the animal kingdom, and also of great significance to developing regenerative medicine. The operculum of serpulid polychaetes ...
Time is of the essence for ParaHox homeobox gene clustering.
(2013-06) - Journal item
ParaHox genes, and their evolutionary sisters the Hox genes, are integral to patterning the anterior-posterior axis of most animals. Like the Hox genes, ParaHox genes can be clustered and exhibit the phenomenon of colinearity ...
A revised spiralian homeobox gene classification incorporating new polychaete transcriptomes reveals a diverse TALE class and a divergent Hox gene
(2018-09-01) - Journal article
The diversity of mechanisms and capacity for regeneration across the Metazoa present an intriguing challenge in evolutionary biology, impacting on the burgeoning field of regenerative medicine. Broad taxonomic sampling is ...
TCF/Lef regulates the Gsx ParaHox gene in central nervous system development in chordates
(2016-03-03) - Journal article
Background The ParaHox genes play an integral role in the anterior-posterior (A-P) patterning of the nervous system and gut of most animals. The ParaHox cluster is an ideal system in which to study the evolution and ...
Annelid Distal-less/Dlx duplications reveal varied post-duplication fates
(2011-08-16) - Journal article
Background: Dlx (Distal-less) genes have various developmental roles and are widespread throughout the animal kingdom, usually occurring as single copy genes in non-chordates and as multiple copies in most chordate genomes. ...
Tunicates push the limits of animal evo-devo
(2011-01-20) - Journal item
The phylum to which humans belong, Chordata, takes its name from one of the major shared derived features of the group, the notochord. All chordates have a notochord, at least during embryogenesis, and there is little doubt ...