Now showing items 1-3 of 3
Studies and application of the enzymes of fluorometabolite biosynthesis in Streptomyces cattleya
(University of St Andrews, 2009) - Thesis,
This thesis focuses on studies investigating the structure of intermediates involved in fluorometabolite biosynthesis, and the potential applications of the fluorinase enzyme in positron emission tomography (PET). Chapter ...
Exploring the substrate scope of the fluorinase from Streptomyces cattleya for applications to positron emission tomography
(University of St Andrews, 2015-11-30) - Thesis,
The fluorinase enzyme, originally isolated from Streptomyces cattleya, has the unique ability to generate a C–F bond from aqueous fluoride ion and S-adenosylmethionine, making the fluorinase an attractive biochemical tool ...
Intermediates and enzymes involved in fluorometabolite biosynthesis in Streptomyces cattleya
(University of St Andrews, 2006) - Thesis,
Enzymatic halogenation occurs during the biosynthesis of more than 4,000 natural products. The presence of fluorinated natural products is much less common, with only 13 reported to date. The bacterium Streptomyces ...