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dc.contributor.authorCote, Caroline L.
dc.contributor.authorCastonguay, Martin
dc.contributor.authorKalujnaia, McWilliam Svetlana
dc.contributor.authorCramb, Gordon
dc.contributor.authorBernatchez, Louis
dc.date.accessioned2014-08-12T10:31:00Z
dc.date.available2014-08-12T10:31:00Z
dc.date.issued2014-05-27
dc.identifier.citationCote , C L , Castonguay , M , Kalujnaia , M S , Cramb , G & Bernatchez , L 2014 , ' In absence of local adaptation, plasticity and spatially varying selection rule : a view from genomic reaction norms in a panmictic species (Anguilla rostrata) ' , BMC Genomics , vol. 15 , 403 . https://doi.org/10.1186/1471-2164-15-403en
dc.identifier.issn1471-2164
dc.identifier.otherPURE: 139790346
dc.identifier.otherPURE UUID: fe26a795-3324-42b2-8e68-37e3502dfe62
dc.identifier.otherWOS: 000338679200001
dc.identifier.otherScopus: 84903546336
dc.identifier.otherWOS: 000338679200001
dc.identifier.otherORCID: /0000-0003-4929-951X/work/64033634
dc.identifier.urihttp://hdl.handle.net/10023/5116
dc.descriptionThis research was funded through the Department of Fisheries and Oceans Canada as well as a Discovery grant from the Natural Sciences and Engineering Research Council of Canada to LB.en
dc.description.abstractBackground: American eel (Anguilla rostrata) is one of the few species for which panmixia has been demonstrated at the scale of the entire species. As such, the development of long term local adaptation is impossible. However, both plasticity and spatially varying selection have been invoked in explaining how American eel may cope with an unusual broad scope of environmental conditions. Here, we address this question through transcriptomic analyses and genomic reaction norms of eels from two geographic origins reared in controlled environments. Results: The null hypothesis of no difference in gene expression between eels from the two origins was rejected. Many unique transcripts and two out of seven gene clusters showed significant difference in expression, both at time of capture and after three months of common rearing. Differences in expression were observed at numerous genes representing many functional groups when comparing eels from a same origin reared under different salinity conditions. Plastic response to different rearing conditions varied among gene clusters with three clusters showing significant origin-environment interactions translating into differential genomic norms of reaction. Most genes and functional categories showing differences between origins were previously shown to be differentially expressed in a study comparing transcription profiles between adult European eels acclimated to different salinities. Conclusions: These results emphasize that while plasticity in expression may be important, there is also a role for local genetic (and/or epigenetic) differences in explaining differences in gene expression between eels from different geographic origins. Such differences match those reported in genetically distinct populations in other fishes, both in terms of the proportion of genes that are differentially expressed and the diversity of biological functions involved. We thus propose that genetic differences between glass eels of different origins caused by spatially varying selection due to local environmental conditions translates into transcriptomic differences (including different genomic norms of reaction) which may in turn explain part of the phenotypic variance observed between different habitats colonized by eels.
dc.format.extent15
dc.language.isoeng
dc.relation.ispartofBMC Genomicsen
dc.rights© 2014 Côté et al.; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.en
dc.subjectAnguillaen
dc.subjectPanmixiaen
dc.subjectTrancriptomeen
dc.subjectMicroarraysen
dc.subjectGenomic reaction normen
dc.subjectPlasticityen
dc.subjectGene-environment interactionsen
dc.subjectConservationen
dc.subjectSt-Lawrence-riveren
dc.subjectTransport protein expressionen
dc.subjectEndangered European eelen
dc.subjectAmerican eelen
dc.subjectGene-expressionen
dc.subjectPhenotypic plasticityen
dc.subjectLife-historyen
dc.subjectHabitat useen
dc.subjectGlass eelen
dc.subjectDevelopmental plasticityen
dc.subjectQH301 Biologyen
dc.subjectBDCen
dc.subjectR2Cen
dc.subject.lccQH301en
dc.titleIn absence of local adaptation, plasticity and spatially varying selection rule : a view from genomic reaction norms in a panmictic species (Anguilla rostrata)en
dc.typeJournal articleen
dc.description.versionPublisher PDFen
dc.contributor.institutionUniversity of St Andrews.School of Medicineen
dc.identifier.doihttps://doi.org/10.1186/1471-2164-15-403
dc.description.statusPeer revieweden


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