Now showing items 1-10 of 32
Identification of 2-aminothiazole-4-carboxylate derivatives active against Mycobacterium tuberculosis H37Rv and the beta-ketoacyl-ACP synthase mtFabH
(2009-05-19) - Journal article
Background: Tuberculosis (TB) is a disease which kills two million people every year and infects approximately over one-third of the world's population. The difficulty in managing tuberculosis is the prolonged treatment ...
Burkholderia pseudomallei genome plasticity associated with genomic island variation
(2008-04-25) - Journal article
Background: Burkholderia pseudomallei is a soil-dwelling saprophyte and the cause of melioidosis. Horizontal gene transfer contributes to the genetic diversity of this pathogen and may be an important determinant of virulence ...
Ephedrine requirements are reduced during spinal anaesthesia for caesarean section in preeclampsia
(Elsevier Ltd., 2005-01) - Journal article
Background: Despite controversy over the haemodynamically safest blockade for caesarean section in women with severe preeclampsia, an increasing number of anaesthetists now opt for spinal anaesthesia. In a previous study ...
Knowlesi malaria in Vietnam
(2009-11-26) - Journal article
The simian malaria parasite Plasmodium knowlesi is transmitted in the forests of Southeast Asia. Symptomatic zoonotic knowlesi malaria in humans is widespread in the region and is associated with a history of spending time ...
Pulse transit time confirms altered haemodynamic response to spinal anaesthesia in pregnancy induced hypertension
(Informa Healthcare, 2002) - Conference item
Attaching and effacing Escherichia coli downregulate DNA mismatch repair protein in vitro and are associated with colorectal adenocarcinomas in humans
(2009-05-13) - Journal article
Background: Mucosa-associated Escherichia coli are frequently found in the colonic mucosa of patients with colorectal adenocarcinoma, but rarely in healthy controls. Chronic mucosal E. coli infection has therefore been ...
Micro-geographic risk factors for malarial infection
(2009-02-13) - Journal article
Background: Knowledge of geography is integral to the study of insect-borne infectious disease such as malaria. This study was designed to evaluate whether geographic parameters are associated with malarial infection in ...
Human immunodeficiency virus seroconversion presenting with acute inflammatory demyelinating polyneuropathy : a case report
(2008-12-04) - Journal article
Introduction: Acute Human Immunodeficiency Virus infection is associated with a range of neurological conditions. Guillain-Barré syndrome is a rare presentation; acute inflammatory demyelinating polyneuropathy is the ...
Identification of a novel class of mammalian phosphoinositol-specific phospholipase C enzymes.
(Spandidos, 2005) - Journal article
Phosphoinositol (PhoIns)-specific phospholipase C enzymes (PLCs) are central to the inositol lipid signaling pathways and contribute to intracellular Ca2+ release and protein kinase C activation. Five distinct classes of ...
Pulse transit time: a new approach to haemodynamic monitoring in obstetric spinal anaesthesia
(Elsevier Ltd., 2002-05) - Conference item