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Functional analysis of the orthobunyavirus nucleocapsid (N) protein
(University of St Andrews, 2008) - Thesis,
Bunyamwera virus (BUNV) is the prototype of the family Bunyaviridae. It has a
tripartite genome consisting of negative sense RNA segments called large (L),
medium (M) and small (S). The S segment encodes the nucleocapsid ...
Sequence analysis of the small (s) RNA segment of viruses in the genus Orthobunyavirus
(University of St Andrews, 2007) - Thesis,
Viruses in the genus Orthobunyavirus (family Bunyaviridae) are classified serologically
into 18 serogroups. The viruses have a tripartite genome of negative sense RNA composed
of large (L), medium (M) and small (S) ...
Impact of interferon β and interferon stimulated gene induction on Bunyamwera virus replication
(University of St Andrews, 2012-06-20) - Thesis,
The first line of defence against viral infection is the interferon (IFN) response, which must be overcome by a virus for successful replication. Pattern recognition receptors detect virus which triggers induction of IFNβ. ...
Attenuation of bunyavirus replication by modification of genomic untranslated regions
(University of St Andrews, 2012-11-30) - Thesis,
Bunyamwera orthobunyavirus (BUNV) is the prototype for the family Bunyaviridae.
BUNV has a tripartite RNA genome of negative polarity composed of the large(L),medium (M)and small(S)segments. Each segment contains an open ...
Structural studies of bunyavirus interferon antagonist proteins
(University of St Andrews, 2016-06-22) - Thesis,
Bunyaviridae is one of the biggest known viral families, and includes many viruses of clinical and economic importance. The major virulence factor of most bunyaviruses is the non-structural protein (NSs). NSs is expressed ...