Now showing items 1-5 of 5
Themed series in organo-fluorine chemistry
(2008-04-25) - Journal item,
Simultaneous feature selection and parameter optimisation using an artificial ant colony : case study of melting point prediction
(2008-10-29) - Journal article,
Background We present a novel feature selection algorithm, Winnowing Artificial Ant Colony (WAAC), that performs simultaneous feature selection and model parameter optimisation for the development of predictive quantitative ...
A novel hybrid ultrafast shape descriptor method for use in virtual screening
(2008-02-18) - Journal article,
Background We have introduced a new Hybrid descriptor composed of the MACCS key descriptor encoding topological information and Ballester and Richards' Ultrafast Shape Recognition (USR) descriptor. The latter one is ...
Biochemical characterization of the initial steps of the Kennedy pathway in Trypanosoma brucei : the ethanolamine and choline kinases
(2008-10-01) - Journal article,
Ethanolamine and choline are major components of the trypanosome membrane phospholipids, in the form of GPEtn (glycero-phosphoethanolamine) and GPCho (glycerophosphocholine). Ethanolamine is also found as an integral ...
An efficient one-step site-directed deletion, insertion, single and multiple-site plasmid mutagenesis protocol
(2008-12-04) - Journal article,
Background: Mutagenesis plays an essential role in molecular biology and biochemistry. It has also been used in enzymology and protein science to generate proteins which are more tractable for biophysical techniques. The ...