Now showing items 1-1 of 1

    • Short-interval observational data to inform clinical trial design in early Huntington’s Disease 

      Hobbs, Nicola Z.; Farmer, Ruth E.; Rees, Elin M.; Cole, James H.; Haider, Salman; Malone, Ian B; Sprengelmeyer, Reiner Heinrich; Johnson, Hans; Mueller, Hans-Peter; Sussmuth, Sigurd D.; Roos, Raymund A.C.; Durr, Alexandra; Frost, Chris; Scahill, Rachael I.; Landwehrmeyer, Bernhard; Tabrizi, Sarah J (2015) - Journal article
      Objectives To evaluate candidate outcomes for disease-modifying trials in Huntington's disease (HD) over 6-month, 9-month and 15-month intervals, across multiple domains. To present guidelines on rapid efficacy readouts ...