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dc.contributor.authorOksuzyan, Anna
dc.contributor.authorSauer, Torsten
dc.contributor.authorGampe, Jutta
dc.contributor.authorHöhn, Andreas
dc.contributor.authorWod, Mette
dc.contributor.authorChristensen, Kaare
dc.contributor.authorWastesson, Jonas W
dc.date.accessioned2021-08-26T12:30:04Z
dc.date.available2021-08-26T12:30:04Z
dc.date.issued2019-05
dc.identifier.citationOksuzyan , A , Sauer , T , Gampe , J , Höhn , A , Wod , M , Christensen , K & Wastesson , J W 2019 , ' Is who you ask important? Concordance between survey and registry data on medication use among self- and proxy-respondents in the longitudinal study of aging Danish twins and the Danish 1905-cohort study ' , Journals of Gerontology Series A - Biological Sciences and Medical Sciences , vol. 74 , no. 5 , pp. 742-747 . https://doi.org/10.1093/gerona/gly104en
dc.identifier.issn1079-5006
dc.identifier.otherPURE: 275393725
dc.identifier.otherPURE UUID: 3b2e760d-f6c8-4660-9deb-2e8feb94b66b
dc.identifier.othercrossref: 10.1093/gerona/gly104
dc.identifier.otherScopus: 85067574378
dc.identifier.otherORCID: /0000-0002-7170-1205/work/98488315
dc.identifier.urihttp://hdl.handle.net/10023/23843
dc.descriptionThis work was supported by the U.S. National Institute of Health (P01AG031719, R01AG026786 and 2P01AG031719), the VELUX Foundation, and the Max Planck Society within the framework of the project “On the edge of societies: New vulnerable populations, emerging challenges for social policies and future demands for social innovation. The experience of the Baltic Sea States (2016–2021).”en
dc.description.abstractBackground This study investigates the accuracy of the reporting of medication use by proxy- and self-respondents, and it compares the prognostic value of the number of medications from survey and registry data for predicting mortality across self- and proxy-respondents. Methods The study is based on the linkage of the Longitudinal Study of Aging Danish Twins and the Danish 1905–Cohort Study with the Danish National Prescription Registry. We investigated the concordance between survey and registry data, and the prognostic value of medication use when assessed using survey and registry data, to predict mortality for self- and proxy-respondents at intake surveys. Results Among self-respondents, the agreement was moderate (κ = 0.52–0.58) for most therapeutic groups, whereas among proxy-respondents, the agreement was low to moderate (κ = 0.36–0.60). The magnitude of the relative differences was, generally, greater among proxies than among self-respondents. Each additional increase in the total number of medications was associated with 7%–8% mortality increase among self- and 4%–6% mortality increase among proxy-respondents in both the survey and registry data. The predictive value of the total number of medications estimated from either data source was lower among proxies (c-statistic = 0.56–0.58) than among self-respondents (c-statistic = 0.74). Conclusions The concordance between survey and registry data regarding medication use and the predictive value of the number of medications for mortality were lower among proxy- than among self-respondents.
dc.language.isoeng
dc.relation.ispartofJournals of Gerontology Series A - Biological Sciences and Medical Sciencesen
dc.rightsCopyright © The Author(s) 2018. Published by Oxford University Press on behalf of The Gerontological Society of America. This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited.en
dc.subjectProxyen
dc.subjectSelf-respondentsen
dc.subjectMedication useen
dc.subjectRegister studyen
dc.subjectDenmarken
dc.subjectRA0421 Public health. Hygiene. Preventive Medicineen
dc.subject3rd-DASen
dc.subject.lccRA0421en
dc.titleIs who you ask important? Concordance between survey and registry data on medication use among self- and proxy-respondents in the longitudinal study of aging Danish twins and the Danish 1905-cohort studyen
dc.typeJournal articleen
dc.description.versionPublisher PDFen
dc.contributor.institutionUniversity of St Andrews.School of Geography & Sustainable Developmenten
dc.identifier.doihttps://doi.org/10.1093/gerona/gly104
dc.description.statusPeer revieweden
dc.identifier.urlhttps://academic.oup.com/biomedgerontology/article/74/5/742/5040076#supplementary-dataen


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