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Modelling cell-cell collision and adhesion with the Filament Based Lamellipodium Model
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dc.contributor.author | Sfakianakis, Nikolaos | |
dc.contributor.author | Peurichard, Diane | |
dc.contributor.author | Brunk, Aaron | |
dc.contributor.author | Schmeiser, Christian | |
dc.date.accessioned | 2019-06-17T16:30:04Z | |
dc.date.available | 2019-06-17T16:30:04Z | |
dc.date.issued | 2018-11-28 | |
dc.identifier | 259100518 | |
dc.identifier | 8803b2fe-5f65-4ae2-8016-0ef4344c8c86 | |
dc.identifier.citation | Sfakianakis , N , Peurichard , D , Brunk , A & Schmeiser , C 2018 , ' Modelling cell-cell collision and adhesion with the Filament Based Lamellipodium Model ' , BIOMATH , vol. 7 , no. 2 , 1811097 . https://doi.org/10.11145/j.biomath.2018.11.097 | en |
dc.identifier.issn | 1314-684X | |
dc.identifier.other | BibCode: 2018arXiv180907852S | |
dc.identifier.other | ORCID: /0000-0002-2675-6338/work/73701865 | |
dc.identifier.uri | https://hdl.handle.net/10023/17908 | |
dc.description | Funding: N.S was partially supported by the German Science Foundation (DFG) under the grant SFB 873 “Maintenance and Differentiation of Stem Cells in Development and Disease”. | en |
dc.description.abstract | We extend the live-cell motility Filament Based Lamellipodium Model to incorporate the forces exerted on the lamellipodium of the cells due to cell-cell collision and cadherin induced cell-cell adhesion. We take into account the nature of these forces via physical and biological constraints and modelling assumptions. We investigate the effect these new components have in the migration and morphology of the cells through particular experiments. We exhibit moreover the similarities between our simulated cells and HeLa cancer cells. | |
dc.format.extent | 14 | |
dc.format.extent | 4338914 | |
dc.language.iso | eng | |
dc.relation.ispartof | BIOMATH | en |
dc.subject | Quantitative biology - cell behavior | en |
dc.subject | QA Mathematics | en |
dc.subject | QH301 Biology | en |
dc.subject | T-NDAS | en |
dc.subject | SDG 3 - Good Health and Well-being | en |
dc.subject.lcc | QA | en |
dc.subject.lcc | QH301 | en |
dc.title | Modelling cell-cell collision and adhesion with the Filament Based Lamellipodium Model | en |
dc.type | Journal article | en |
dc.contributor.institution | University of St Andrews. Applied Mathematics | en |
dc.identifier.doi | https://doi.org/10.11145/j.biomath.2018.11.097 | |
dc.description.status | Peer reviewed | en |
dc.identifier.url | http://adsabs.harvard.edu/abs/2018arXiv180907852S | en |
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