Now showing items 1-10 of 106
A perspective on multi-target drug discovery and design for complex diseases
(2018-01-17) - Journal item,
Diseases of infection, of neurodegeneration (such as Alzheimer’s and Parkinson’s diseases), and of malignancy (cancers) have complex and varied causative factors. Modern drug discovery has the power to identify potential ...
Direct and indirect approaches to identify drug modes of action
(2018-01) - Journal item,
Phenotypic assays are becoming increasingly more common among drug discovery practices, expanding drug target diversity as lead compounds identified through such screens are not limited to known targets. While increasing ...
The evolutionary ecology of the Lygaeidae
(2014-06) - Journal item,
The Lygaeidae (sensu lato) are a highly successful family of true bugs found worldwide, yet many aspects of their ecology and evolution remain obscure or unknown. While a few species have attracted considerable attention ...
Beyond sex allocation : the role of mating systems in sexual selection in parasitoid wasps
(2015-05) - Journal item,
Despite the diverse array of mating systems and life histories which characterise the parasitic Hymenoptera, sexual selection and sexual conflict in this taxon have been somewhat overlooked. For instance, parasitoid mating ...
Specialized membrane domains of plasmodesmata, plant intercellular nanopores
(2014-09-30) - Journal item,
More on the genetical theory of multilevel selection
(2015) - Journal item,
In my article The genetical theory of multilevel selection, I provided a synthesis of the theory of multilevel selection (MLS) and the theory of natural selection in class-structured populations. I framed this synthesis ...
(2015-08) - Journal item,
The first American Naturalist appeared in March 1867. In a countdown to the 150th anniversary, the editors have solicited short commentaries on articles from the past that deserve a second look.
Effects of salmon lice Lepeophtheirus salmonis on wild sea trout Salmo trutta – a literature review
(2015-08-20) - Journal item,
Salmon farming increases the abundance of salmon lice, which are ectoparasites of salmonids in the sea. Here we review the current knowledge on the effects of salmon lice on wild sea trout. Salmon lice feed on host mucus, ...
Organizing, supporting and linking the world marine biodiversity research community
(2015-02-10) - Journal item,
The evolutionary ecology of decorating behaviour
(2015-06) - Journal item,
Many animals decorate themselves through the accumulation of environmental material on their exterior. Decoration has been studied across a range of different taxa, but there are substantial limits to current understanding. ...