Now showing items 1-2 of 2

    • PRIMA-1Met suppresses colorectal cancer independent of p53 by targeting MEK 

      Lu, Tao; Zou, Yanmei; Xu, Guogang; Potter, Jane A.; Taylor, Garry L.; Duan, Qiuhong; Yang, Qin; Xiong, Huihua; Qiu, Hong; Ye, Dawei; Zhang, Peng; Yu, Shiying; Yuan, Xianglin; Zhu, Feng; Wang, Yihua; Xiong, Hua (2016-10-27) - Journal article
      PRIMA-1Met is the methylated PRIMA-1 (p53 reactivation and induction of massive apoptosis) and could restore tumor suppressor function of mutant p53 and induce p53 dependent apoptosis in cancer cells harboring mutant p53. ...
    • Structural studies on the sialidases from Streptococcus pneumoniae and Pseudomonas aeruginosa 

      Xu, Guogang (University of St Andrews, 2009) - Thesis
      The sialidases are a group of glycosyl hydrolases that specifically remove terminal sialic acid (Neu5Ac) residues from various glycans. In the two common human pathogenic bacteria Streptococcus pneumoniae and Pseudomonas ...