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  • Multitarget-directed ligands combining cholinesterase and monoamine oxidase inhibition with histamine H3R antagonism for neurodegenerative diseases 

    Bautista-Aguilera, Óscar M.; Hagenow, Stefanie; Palomino-Antolin, Alejandra; Farré-Alins, Víctor; Ismaili, Lhassane; Joffrin, Pierre-Louis; Jimeno, María L.; Soukup, Ondřej; Janočková, Jana; Kalinowsky, Lena; Proschak, Ewgenij; Iriepa, Isabel; Moraleda, Ignacio; Schwed, Johannes S.; Romero Martínez, Alejandro; López-Muñoz, Francisco; Chioua, Mourad; Egea, Javier; Ramsay, Rona R.; Marco-Contelles, José; Stark, Holger (2017-10-02) - Journal article
    The therapy of complex neurodegenerative diseases requires the development of multitarget-directed drugs (MTDs). Novel indole derivatives with inhibitory activity towards acetyl/butyrylcholinesterases and monoamine oxidases ...