Now showing items 1-2 of 2

  • Interferon, viruses and drug discovery 

    Gage, Zoe O. (University of St Andrews, 2017-06-21) - Thesis
    The interferon (IFN) response is a crucial component of cellular innate immunity, vital for controlling virus infections. Dysregulation of the IFN response however can lead to serious medical conditions including autoimmune ...
  • Modular cell-based platform for high throughput identification of compounds that inhibit a viral interferon antagonist of choice 

    Vasou, Andri; Paulus, Christina; Narloch, Janina; Gage, Zoe O.; Rameix-Welti, Marie-Anne; Eléouët, Jean-François; Nevels, Michael; Randall, Richard E.; Adamson, Catherine S. (2018-02) - Journal article
    Viral interferon (IFN) antagonists are a diverse class of viral proteins that counteract the host IFN response, which is important for controlling viral infections. Viral IFN antagonists are often multifunctional proteins ...