Browsing Biology (School of) by Subject "XBP1"
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Endoplasmic Reticulum Degradation–Enhancing α-Mannosidase–like Protein 1 targets misfolded HLA–B27 dimers for Endoplasmic Reticulum–Associated Degradation (2014-11) - Journal articleObjective. HLA-B27 forms misfolded heavy chain dimers, which may predispose individuals to inflammatory arthritis by inducing endoplasmic reticulum (ER) stress and the unfolded protein response (UPR). We wanted to define ...