Now showing items 1-17 of 17

    • Actin turnover is required for myosin-dependent mitochondrial movements in Arabidopsis root hairs 

      Zheng, Maozhong; Beck, Martina; Muller, Jens; Wang, Xiaohua; Wang, Qinli; Baluska, Frantisek; Logan, David; Samaj, Jozef; Lin, Jinxing (2009-06) - Journal article
      Background: Previous studies have shown that plant mitochondrial movements are myosin-based along actin filaments, which undergo continuous turnover by the exchange of actin subunits from existing filaments. Although earlier ...
    • Blocking Variant Surface Glycoprotein synthesis in Trypanosoma brucei triggers a general arrest in translation initiation 

      Smith, Terry K; Vasileva, Nadina; Gluenz, Eva; Terry, Stephen; Portman, Neil; Kramer, Susanne; Carrington, Mark; Michaeli, Shulamit; Gull, Keith; Rudenko, Gloria (2009-10-26) - Journal article
      Background: The African trypanosome Trypanosoma brucei is covered with a dense layer of Variant Surface Glycoprotein (VSG), which protects it from lysis by host complement via the alternative pathway in the mammalian ...
    • Clicking in Shallow Rivers : Short-Range Echolocation of Irrawaddy and Ganges River Dolphins in a Shallow, Acoustically Complex Habitat 

      Jensen, Frants; Rocco, Alice; Mansur, Rubaiyat; Smith, Brian; Janik, Vincent M.; Madsen, Peter (2013-04-03) - Journal article
      Toothed whales (Cetacea, odontoceti) use biosonar to navigate their environment and to find and catch prey. All studied toothed whale species have evolved highly directional, high-amplitude ultrasonic clicks suited for ...
    • Exploring the ultrashort pulse laser parameter space for membrane permeabilisation in mammalian cells. 

      Rudhall, Andrew Peter; Antkowiak, Maciej; Tsampoula, Xanthi; Mazilu, Michael; Metzger, N Klaus; Gunn-Moore, Frank J; Dholakia, Kishan (2012) - Journal article
      The use of ultrashort femtosecond pulsed lasers to effect membrane permeabilisation and initiate both optoinjection and transfection of cells has recently seen immense interest. We investigate femtosecond laser-induced ...
    • Female rose bitterling prefer MHC-dissimilar males : experimental evidence 

      Reichard, Martin; Spence, Rowena Grace Alison; Bryjova, Anna; Bryja, Pepa; Smith, Carl (2012-07-18) - Journal article
      The role of genetic benefits in female mate choice remains a controversial aspect of sexual selection theory. In contrast to “good allele” models of sexual selection, “compatible allele” models of mate choice predict that ...
    • Femtosecond optoinjection of intact tobacco BY-2 cells using a reconfigurable photoporation platform 

      Mitchell, C.A.; Kalies, S.; Cizmár, T.; Heisterkamp, A.; Torrance, L.; Roberts, A.G.; Gunn-Moore, F.J.; Dholakia, K. (2013-11-14) - Journal article
      A tightly-focused ultrashort pulsed laser beam incident upon a cell membrane has previously been shown to transiently increase cell membrane permeability while maintaining the viability of the cell, a technique known as ...
    • Following a foraging fish-finder : Diel habitat use of Blainville's beaked whales revealed by echolocation 

      Arranz, Patricia; Aguilar de Soto, Natacha; Madsen, Peter T.; Brito, Alberto; Bordes, Fernando; Johnson, Mark P. (2011-12-07) - Journal article
      Simultaneous high resolution sampling of predator behavior and habitat characteristics is often difficult to achieve despite its importance in understanding the foraging decisions and habitat use of predators. Here we tap ...
    • The inexorable spread of a newly arisen neo-Y chromosome 

      Veltsos, Paris; Keller, I; Nichols, R A (2008-05) - Journal article
      A newly arisen Y-chromosome can become established in one part of a species range by genetic drift or through the effects of selection on sexually antagonistic alleles. However, it is difficult to explain why it should ...
    • Influenza virus A infection of human monocyte and macrophage subpopulations reveals increased susceptibility associated with cell differentiation 

      Hoeve, Marieke A.; Nash, Anthony A.; Jackson, David; Randall, Richard E.; Dransfield, Ian (2012-01-04) - Journal article
      Influenza virus infection accounts for significant morbidity and mortality world-wide. Interactions of the virus with host cells, particularly those of the macrophage lineage, are thought to contribute to various pathological ...
    • Interspecific synchrony of seabird population growth rate and breeding success 

      Robinson, James P. W.; Dornelas, Maria; Ojanguren, Alfredo Fernandez (2013) - Journal article
      Environmental variability can destabilize communities by causing correlated interspecific fluctuations that weaken the portfolio effect, yet evidence of such a mechanism is rare in natural systems. Here, we ask whether the ...
    • Novel bacteriophages containing a genome of another bacteriophage within their genomes 

      Swanson, Maud M.; Reavy, Brian; Makarova, Kira S.; Cock, Peter J.; Hopkins, David W.; Torrance, Lesley; Koonin, Eugene V.; Taliansky, Michael (2012-07-17) - Journal article
      A novel bacteriophage infecting Staphylococus pasteuri was isolated during a screen for phages in Antarctic soils. The phage named SpaA1 is morphologically similar to phages of the family Siphoviridae. The 42,784 bp genome ...
    • PELDOR in rotationally symmetric homo-oligomers 

      Giannoulis, Angeliki; Ward, Richard James; Branigan, Emma; Naismith, Jim; Bode, Bela Ernest (2013) - Journal article
      Nanometre distance measurements by pulsed electron−electron double resonance (PELDOR) spectroscopy have become an increasingly important tool in structural biology. The theoretical underpinning of the experiment is ...
    • RNA interference targets arbovirus replication in Culicoides cells 

      Schnettler, Esther; Ratinier, Maxime; Watson, Mick; Shaw, Andrew E.; McFarlane, Melanie; Varela, Mariana; Elliott, Richard M.; Palmarini, Massimo; Kohl, Alain (2013-03) - Journal article
      Arboviruses are transmitted to vertebrate hosts by biting arthropod vectors such as mosquitoes, ticks, and midges. These viruses replicate in both arthropods and vertebrates and are thus exposed to different antiviral ...
    • The stabilisation potential of individual and mixed assemblages of natural bacteria and microalgae 

      Lubarsky, Helen V.; Hubas, Cedric; Chocholek, Melanie; Larson, Fredrik; Manz, Werner; Paterson, David M.; Gerbersdorf, Sabine U. (2010-11-02) - Journal article
      It is recognized that microorganisms inhabiting natural sediments significantly mediate the erosive response of the bed ("ecosystem engineers") through the secretion of naturally adhesive organic material (EPS: extracellular ...
    • Structure-function study of mammalian Munc18-1 and C. elegans UNC-18 implicates domain 3b in the regulation of exocytosis 

      Graham, Margaret E.; Prescott, Gerald R.; Johnson, James R.; Jones, Mathew; Walmesley, Alice; Haynes, Lee P.; Morgan, Alan; Burgoyne, Robert D.; Barclay, Jeff W. (2011-03-21) - Journal article
      Munc18-1 is an essential synaptic protein functioning during multiple stages of the exocytotic process including vesicle recruitment, docking and fusion. These functions require a number of distinct syntaxin-dependent ...
    • Time is of the essence for ParaHox homeobox gene clustering. 

      Garstang, Myles Grant; Ferrier, David Ellard Keith (2013-06) - Journal item
      ParaHox genes, and their evolutionary sisters the Hox genes, are integral to patterning the anterior-posterior axis of most animals. Like the Hox genes, ParaHox genes can be clustered and exhibit the phenomenon of colinearity ...
    • Wavefront corrected light sheet microscopy in turbid media 

      Dalgarno, Heather Isla Campbell; Cizmar, Tomas; Vettenburg, Tom; Nylk, Jonathan; Gunn-Moore, Frank J; Dholakia, Kishan (2012-05) - Journal article
      Light sheet microscopy is a powerful method for three-dimensional imaging of large biological specimens. However, its imaging ability is greatly diminished by sample scattering and aberrations. Optical clearing, Bessel ...