Now showing items 1-2 of 2

    • An investigation of NAADP-dependent Ca²⁺ signalling mechanisms in arterial smooth muscle 

      Kinnear, Nicholas P. (University of St Andrews, 2007-11-30) - Thesis
      Previous investigations on pulmonary artery smooth muscle cells have shown that nicotinic acid adenine dinucleotide diphosphate (NAADP) evokes highly localised intracellular Ca²⁺ bursts by mobilising thapsigargin-insensitive ...
    • Two-pore channels and NAADP-dependent calcium signalling 

      Calcraft, Peter James (University of St Andrews, 2010-06-23) - Thesis
      Nicotinic acid adenine dinucleotide phosphate (NAADP) is a potent Ca²⁺ mobilising messenger in mammalian and non-mammalian cells. Studies on a variety of cell types suggest that NAADP evokes Ca²⁺ release from a lysosome-related ...