Now showing items 1-2 of 2

    • CRISPR RNA biogenesis by a Cas6 nuclease 

      Sokolowski, Richard D. (University of St Andrews, 2015-06-24) - Thesis
      Clustered regularly interspaced short palindromic repeats (CRISPRs) and associated (Cas) proteins form the basis of a prokaryotic adaptive immune system. Acquired sections of viral DNA are stored within the host genome as ...
    • Memories are made of this : investigating the CRISPR-Cas adaption mechanism 

      Rollie, Clare (University of St Andrews, 2017-06-21) - Thesis
      CRISPR-Cas is an adaptive immune system unique to prokaryotes, which prevents infection by foreign genetic elements. Key to the function of CRISPR-Cas immunity is the ability to adapt to new threats in incorporating short ...