Now showing items 1-4 of 4
The contribution of the subthalamic nucleus to executive functions in rat
(University of St Andrews, 2014-12-01) - Thesis,
Lesions of the subthalamic nucleus (STN) alleviate the cardinal signs of idiopathic as well as MPTP-induced Parkinson’s disease in primates. For this reason, the STN is a target for clinical treatment of Parkinson’s ...
An evaluation of cognitive deficits in a rat-model of Huntington's disease
(University of St Andrews, 2016-06-21) - Thesis,
The purpose of this thesis was to develop methodology by which treatments for the cognitive impairments in Huntington’s disease (HD) could be tested. As such, the thesis focused mainly on evaluating rats with quinolinic ...
Learning to focus and focusing to learn : more than a cortical trick
(University of St Andrews, 2018-12-06) - Thesis,
The consequence of many psychiatric and neurodegenerative disorders, such as Parkinson’s disease and schizophrenia, is an impairment in ‘executive functioning’; an umbrella term for several cognitive processes, including ...
Attention regulation and behavioural flexibility in rats with relevance to schizophrenia
(University of St Andrews, 2017-06-20) - Thesis,
Schizophrenia is a neuropsychological disorder in which the neural systems which regulate attention allocation, primarily the dorsolateral prefrontal cortex, are dysfunctional, resulting in deficient gating of attention ...