Now showing items 1-2 of 2
An evaluation of cognitive deficits in a rat-model of Huntington's disease
(University of St Andrews, 2016-06-21) - Thesis,
The purpose of this thesis was to develop methodology by which treatments for the cognitive impairments in Huntington’s disease (HD) could be tested. As such, the thesis focused mainly on evaluating rats with quinolinic ...
In vivo and in vitro studies of positive allosteric modulation of the NMDA receptor
(University of St Andrews, 2017-06-20) - Thesis,
Dysfunction of the N-methyl-D-aspartate (NMDA) receptor is thought to contribute to the cognitive deficits of many neurodegenerative diseases and psychiatric disorders. Cognitive symptoms of Alzheimer’s disease can be ...