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dc.contributor.authorSioriki, Eleni
dc.contributor.authorSmith, Terry K.
dc.contributor.authorDemopoulos, Constantinos A.
dc.contributor.authorZabetakis, Ioannis
dc.date.accessioned2017-03-11T00:32:54Z
dc.date.available2017-03-11T00:32:54Z
dc.date.issued2016-05
dc.identifier.citationSioriki , E , Smith , T K , Demopoulos , C A & Zabetakis , I 2016 , ' Structure and cardioprotective activities of polar lipids of olive pomace, olive pomace-enriched fish feed and olive pomace fed gilthead sea bream ( Sparus aurata ) ' , Food Research International , vol. 83 , pp. 143-151 . https://doi.org/10.1016/j.foodres.2016.03.015en
dc.identifier.issn0963-9969
dc.identifier.otherPURE: 241555047
dc.identifier.otherPURE UUID: 155110ad-8ec8-401d-9cb4-1f2a5bc80c91
dc.identifier.otherRIS: urn:C86FF63BFB729B9C3D15809BE63143FD
dc.identifier.otherScopus: 84960457271
dc.identifier.otherWOS: 000374801100014
dc.identifier.urihttps://hdl.handle.net/10023/10453
dc.descriptionThis work is supported in part by the aquaculture company NIREUS SA and TKS's Wellcome Trust project grant 093228.en
dc.description.abstractTotal lipids of olive pomace (OP), olive pomace diet (OP diet), fish oil diet (FO diet) and fish filets of farmed gilthead sea bream (fish fed with FO diet and OP diet respectively) were extracted and separated into polar (TPL) and neutral (TNL) lipids. All samples were assessed for their in vitro activity against washed rabbit platelets aggregation induced by platelet activating factor (PAF) and they were further analyzed by electrospray-mass spectrometry. The high levels of palmitic (16:0), oleic (18:1 cis ω − 9), linoleic (18:2 ω − 6) and docosapentaenoic acid (DPA 22:5 ω − 3) contained in both OP and FO diets are reflected to the gilthead sea breams fed with the individual diet respectively, while the gilthead sea bream fed with FO diet displays a decrease in DPA. All samples contained various glycerophospholipids species. Two PE species were identified in OP, OP diet and fish fed with OP diet and not in FO diet, while that might be an indication that these substances are likely to be the key polar phospholipids that have the ability to be in vitro PAF inhibitors, i.e. inhibit the formation of atherosclerotic plaques in blood arteries.
dc.language.isoeng
dc.relation.ispartofFood Research Internationalen
dc.rights© 2016, Elsevier. This work is made available online in accordance with the publisher’s policies. This is the author created, accepted version manuscript following peer review and may differ slightly from the final published version. The final published version of this work is available at www.sciencedirect.com / https://dx.doi.org/10.1016/j.foodres.2016.03.015en
dc.subjectGilthead sea bream (Sparus aurata)en
dc.subjectOlive pomaceen
dc.subjectCardioprotective propertiesen
dc.subjectTandem mass spectrometryen
dc.subjectGlycerophospholipidsen
dc.subjectQH301 Biologyen
dc.subjectQD Chemistryen
dc.subject.lccQH301en
dc.subject.lccQDen
dc.titleStructure and cardioprotective activities of polar lipids of olive pomace, olive pomace-enriched fish feed and olive pomace fed gilthead sea bream (Sparus aurata)en
dc.typeJournal articleen
dc.contributor.sponsorThe Wellcome Trusten
dc.description.versionPostprinten
dc.contributor.institutionUniversity of St Andrews. School of Biologyen
dc.contributor.institutionUniversity of St Andrews. Biomedical Sciences Research Complexen
dc.identifier.doihttps://doi.org/10.1016/j.foodres.2016.03.015
dc.description.statusPeer revieweden
dc.date.embargoedUntil2017-03-10
dc.identifier.grantnumber093228/Z/10/Zen


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