Now showing items 1-3 of 3

  • 2A-induced ribosome stalling 

    Odon, Valèrie M. N. (University of St Andrews, 2014-06-25) - Thesis
    Originally 2A was characterised in foot-and-mouth disease virus. Site directed mutagenesis identified a C-terminus consensus motif [D(V/I)ExNPGP] and it is proposed that 2A interacts with the exit tunnel of the ribosome ...
  • The evolution and regulation of the chordate ParaHox cluster 

    Garstang, Myles Grant (University of St Andrews, 2016-06-22) - Thesis
    The ParaHox cluster is the evolutionary sister of the Hox cluster. Like the Hox cluster, the ParaHox cluster is subject to complex regulatory phenomena such as collinearity. Despite the breakup of the ParaHox cluster within ...
  • TCF/Lef regulates the Gsx ParaHox gene in central nervous system development in chordates 

    Garstang, Myles Grant; Osborne, Peter; Ferrier, David Ellard Keith (2016-03-03) - Journal article
    Background The ParaHox genes play an integral role in the anterior-posterior (A-P) patterning of the nervous system and gut of most animals. The ParaHox cluster is an ideal system in which to study the evolution and ...