Now showing items 2287-2306 of 11912

  • Design, implementation and deployment of state machines using a generative approach 

    Kirby, Graham Njal Cameron; Dearle, Alan; Norcross, Stuart John (Springer, 2008) - Book item
    We describe an approach to designing and implementing a distributed system as a family of related finite state machines, generated from a single abstract model. Various artefacts are generated from each state machine, ...
  • Design, synthesis and in vitro evaluation of benzothiazole-based ureas as potential ABAD/17β-HSD10 modulators for Alzheimer’s disease treatment 

    Hroch, Lukas; Benek, Ondrej; Guest, Patrick; Aitken, Laura; Soukup, Ondrej; Janockova, Jana; Musil, Karel; Dohnal, Vlastimil; Dolezal, Rafael; Kuca, Kamil; Smith, Terry K; Gunn-Moore, Frank J; Musilek, K (2016-08-01) - Journal item
    Amyloid-beta peptide (Aβ) has been recognized to interact with numerous proteins, which may lead to pathological changes in cell metabolism of Alzheimer’s disease (AD) patients. One such known metabolic enzyme is mitochondrial ...
  • Design, synthesis and in vitro evaluation of indolotacrine analogues as multi-target-directed ligands for the treatment of Alzheimer’s disease 

    Benek, Ondrej; Soukup, Ondrej; Pasdiorova, Marketa; Hroch, Lukas; Sepsova, Vendula; Jost, Petr; Hrabinova, Martina; Jun, Daniel; Kuca, Kamil; Zala, Dominykas; Ramsay, Rona R.; Marco-Contelles, José; Musilek, Kamil (2016-06-20) - Journal article
    In this study, novel indolotacrine analogues have been designed, synthesized and evaluated as potential drugs for the treatment of Alzheimer’s disease. Based on a multi-target-directed ligand approach, novel compounds have ...
  • Designing a shipboard line transect survey to estimate cetacean abundance off the Azores Archipelago, Portugal 

    Faustino, Cláudia Estevinho Santos (2008) - Thesis
    Management schemes dedicated to the conservation of wildlife populations rely on the effective monitoring of population size, and this requires the accurate and precise estimation of abundance. The accuracy and precision ...
  • Designing hypercyclic replicating networks 

    Wood, Evan A. (University of St Andrews, 2007-11-30) - Thesis
    In the last 20 years there has been a number of synthetic and natural product based molecular replicators published in the literature. The majority of these systems have focused on the minimal model with only a few examples ...
  • Designing spin-channel geometries for entanglement distribution 

    Levi, Elliott Kendrick; Kirton, Peter George; Lovett, Brendon William (2016-09-01) - Journal article
    We investigate different geometries of spin-1/2 nitrogen impurity channels for distributing entanglement between pairs of remote nitrogen vacancy centers (NVs) in diamond. To go beyond the system size limits imposed by ...
  • Designing the Unexpected : Endlessly Fascinating Interaction for Interactive Installations 

    MacDonald, Lindsay; Brosz, John; Nacenta, Miguel; Carpendale, Sheelagh (ACM, 2015-01-15) - Conference item
    We present A Delicate Agreement, an interactive art installation designed to intrigue viewers by offering them an unfolding story that is endlessly fascinating. To achieve this, we set our story in the liminal space of an ...
  • DESNT : a poor prognosis category of human prostate cancer 

    Luca, Bogdan-Alexandru; Brewer, Daniel S.; Edwards, Dylan R.; Edwards, Sandra; Whitaker, Hayley C.; Merson, Sue; Dennis, Nening; Cooper, Rosalin A.; Hazell, Steven; Warren, Anne Y.; Eeles, Rosalind; Lynch, Andy G.; Ross-Adams, Helen; Lamb, Alastair D.; Neal, David E.; Sethia, Krishna; Mills, Robert D.; Ball, Richard Y.; Curley, Helen; Clark, Jeremy; Moulton, Vincent; Cooper, Colin S. (2017-03-06) - Journal article
    Background : A critical problem in the clinical management of prostate cancer is that it is highly heterogeneous. Accurate prediction of individual cancer behaviour is therefore not achievable at the time of diagnosis ...
  • Destruction and redemption : the conduct of revealed religious violence in the contemporary era 

    Muir, Angus (University of St Andrews, 2001) - Thesis
    The final quarter of the twentieth century saw the emergence of a variety of security threats, perhaps the most pernicious and least understood of which has been the rise of religiously motivated violence and terrorism. ...
  • A detailed census of variable stars in the globular cluster NGC 6333 (M9) from CCD differential photometry 

    Arellano Ferro, A.; Bramich, D. M.; Figuera Jaimes, Roberto Jose; Giridhar, Sunetra; Kains, N.; Kuppuswamy, K.; Jorgensen, U. G.; Alsubai, K. A.; Andersen, J. M.; Bozza, V.; Browne, Paul; Calchi Novati, S.; Damerdji, Y.; Diehl, C.; Dominik, Martin; Dreizler, S.; Elyiv, A.; Giannini, E.; Harpsoe, K.; Hessman, F. V.; Hinse, T. C.; Hundertmark, Markus Peter Gerhard; Juncher, D.; Kerins, E.; Korhonen, H.; Liebig, Christine Elisabeth; Mancini, L.; Mathiasen, M.; Penny, M. T.; Rabus, M.; Rahvar, S.; Ricci, D.; Scarpetta, G.; Skottfelt, J.; Snodgrass, C.; Southworth, J.; Surdej, J.; Tregloan-Reed, J.; Vilela, C.; Wertz, O. (2013-09-11) - Journal article
    We report CCD V and I time series photometry of the globular cluster NGC 6333 (M9). The technique of difference image analysis has been used, which enables photometric precision better than 0.05 mag for stars brighter than ...
  • A detailed chemical and petrological investigation of the rocks of the Shiant Isles 

    Murray, Ransom James (University of St Andrews, 1953) - Thesis
  • A detailed investigation of the properties of a Vlasov-Maxwell equilibrium for the force-free Harris sheet 

    Neukirch, Thomas; Wilson, F.; Harrison, M. G. (2009-12) - Journal article
    A detailed discussion is presented of the Vlasov-Maxwell equilibrium for the force-free Harris sheet recently found by Harrison and Neukirch [Phys. Rev. Lett. 102, 135003 (2009)]. The derivation of the distribution function ...
  • Detectability in audio-visual surveys of tropical rainforest birds : the influence of species, weather and habitat characteristics 

    Anderson, Alexander S.; Marques, Tiago A.; Shoo, Luke P.; Williams, Stephen E. (2015-06-25) - Journal article
    Indices of relative abundance do not control for variation in detectability, which can bias density estimates such that ecological processes are difficult to infer. Distance sampling methods can be used to correct for ...
  • Detecting a visual object in the presence of other objects : the flanker facilitation effect in contour integration 

    Gillespie, Christopher (University of St Andrews, 2015) - Thesis
    When an observer views a complex visual scene and tries to identify an object, his or her visual system must decide what regions of the visual field correspond to the object of interest and which do not. One aspect of ...
  • Detecting abnormal events on binary sensors in smart home environments 

    Ye, Juan; Stevenson, Graeme; Dobson, Simon (2016-12) - Journal article
    With a rising ageing population, smart home technologies have been demonstrated as a promising paradigm to enable technology-driven healthcare delivery. Smart home technologies, composed of advanced sensing, computing, and ...
  • Detecting adaptive evolution based on association with ecological gradients : orientation matters 

    Frichot, Eric; Schoville, Sean; Pierre, de Villemereuil; Gaggiotti, Oscar Eduardo; Francois, Olivier (2015-07) - Journal article
    Population genetic signatures of local adaptation are frequently investigated by identifying loci with allele frequencies that exhibit high correlation with ecological variables. One difficulty with this approach is that ...
  • Detecting cryptic indirect genetic effects 

    Bailey, Nathan William; Hoskins, Jessica L. (2014-07) - Journal article
    Indirect genetic effects (IGEs) occur when genes expressed in one individual alter the phenotype of an interacting partner. IGEs can dramatically affect the expression and evolution of social traits. However, the interacting ...
  • Detecting gamma frequency neural activity using simultaneous multiband EEG-fMRI 

    Uji, Makoto; Wilson, Ross; Francis, Susan; Mullinger, Karen; Mayhew, Stephen (2017-06-26) - Conference poster
    Synchronization of gamma frequency (>35Hz) EEG activity is linked to cognitive and sensory behaviour as well as being widely cited as the closest neuronal correlate of the BOLD fMRI signal[1]. However, the majority of ...
  • Detecting gamma frequency neural activity using simultaneous multiband EEG-fMRI 

    Uji, Makoto; Wilson, Ross; Francis, Susan; Mullinger, Karen; Mayhew, Stephen (2017-06-26) - Conference item
    Synchronization of gamma frequency (>35Hz) EEG activity is linked to cognitive and sensory behaviour as well as being widely cited as the closest neuronal correlate of the BOLD fMRI signal[1]. However, the majority of ...
  • Detecting gamma frequency neural activity using simultaneous multiband EEG-fMRI 

    Uji, Makoto; Wilson, Ross; Francis, Susan; Mayhew, Stephen; Mullinger, Karen (2017-04) - Conference item
    Synopsis (≤ 100 words): We establish a methodology for optimal combination of simultaneous EEG recording with sparse multiband fMRI that preserves high resolution, whole brain fMRI coverage with broad-band EEG signal ...