Now showing items 2157-2176 of 8377

  • Efficient genome engineering of Toxoplasma gondii using CRISPR/Cas9 

    Sidik, Saima M.; Hackett, Caroline G.; Tran, Fanny; Westwood, Nicholas J.; Lourido, Sebastian (2014-06-27) - Journal article
    Toxoplasma gondii is a parasite of humans and animals, and a model for other apicomplexans including Plasmodium spp., the causative agents of malaria. Despite many advances, manipulating the T. gondii genome remains labor ...
  • Efficient light-emitting electrochemical cells using small molecular weight, ionic, host-guest systems 

    Pertegás, Antonio; Wong, Michael Yin; Sessolo, Michele; Zysman-Colman, Eli; Bolink, Henk J. (2016) - Journal article
    Light-emitting electrochemical cells (LECs) based on fluorescent host-guest small molecules system are reported. The LECs show electroluminescence coming solely from the guest, with an external quantum efficiency (EQE) of ...
  • An efficient method for the in vitro production of Azol(in)e-based cyclic peptides 

    Houssen, W.E.; Bent, A.F.; McEwan, A.R.; Pieiller, N.; Tabudravu, J.; Koehnke, J.; Mann, G.; Adaba, R.I.; Thomas, L.; Hawas, U.W.; Liu, H.; Schwarz-Linek, U.; Smith, M.C.M.; Naismith, J.H.; Jaspars, M. (2014-12-15) - Journal article
    Heterocycle-containing cyclic peptides are promising scaffolds for the pharmaceutical industry but their chemical synthesis is very challenging. A new universal method has been devised to prepare these compounds by using ...
  • Efficient monitoring of large scale infrastructure as a service clouds 

    Ward, Jonathan Stuart (University of St Andrews, 2015) - Thesis
    Cloud computing has had a transformative effect upon distributed systems research. It has been one of the precursors of supposed big data revolution and has amplified the scale of software, networks, data and ...
  • Efficient nash equilibrium under adverse selection 

    Diasakos, Theodoros; Koufopoulos, Kostas (University of St Andrews, 2013-08) - Working or discussion paper
    This paper revisits the problem of adverse selection in the insurance market of Rothschild and Stiglitz (QJE, 1976). We propose a simple extension of the game-theoretic structure in Hellwig (EER, 1987) under which Nash-type ...
  • An efficient one-step site-directed deletion, insertion, single and multiple-site plasmid mutagenesis protocol 

    Liu, Huanting; Naismith, James Henderson (2008-12-04) - Journal article
    Background: Mutagenesis plays an essential role in molecular biology and biochemistry. It has also been used in enzymology and protein science to generate proteins which are more tractable for biophysical techniques. The ...
  • Efficient phagocytosis and laccase activity affect the outcome of HIV-associated cryptococcosis 

    Sabiiti, Wilber; Robertson, Emma; Beale, Mathew A; Johnston, Simon A; Brouwer, Annemarie E; Loyse, Angela; Jarvis, Joseph N; Gilbert, Andrew S; Fisher, Matthew C; Harrison, Thomas S; May, Robin C; Bicanic, Tihana (2014-05-01) - Journal article
    Background. Cryptococcal meningitis (CM) is a leading cause of HIV-associated mortality globally. High fungal burden in cerebrospinal fluid (CSF) at diagnosis and poor fungal clearance during treatment are recognized adverse ...
  • An efficient route for the synthesis of phosphorus-selenium macro-heterocycles 

    Hua, Guoxiong; Slawin, Alexandra M. Z.; Randall, Rebecca A. M.; Cordes, David B.; Crawford, Luke; Buehl, Michael; Woollins, J. Derek (2013-04) - Journal article
    Four-membered ring [PhP(Se)(mu-Se)](2) (Woollins' reagent, WR) reacts with disodium alkenyl-diols followed by in situ ring-closure reaction with appropriate dibromoalkanes affording a series of unusual nine-to fifteen-membered ...
  • Efficient single photon collection using a μ-fiber-coupled microcavity 

    Lee, Chang Min; Lim, Hee Jin; Schneider, Christian; Maier, Sebastian; Höfling, Sven; Kamp, Martin; Lee, Yong Hee (IEEE, 2016-01-07) - Conference item
    Efficient single photon collection is demonstrated based on a μ-fiber-coupled photonic crystal cavity. 249 kHz of single photons are detected, and estimated single photon count rate (overall collection efficiency) is 20 ...
  • Efficient single photon source based on μ-fibre-coupled tunable microcavity 

    Lee, C.-M.; Lim, H.-J.; Schneider, C.; Maier, S.; Höfling, Sven; Kamp, M.; Lee, Y.-H. (2015-09-22) - Journal article
    Efficient and fast on-demand single photon sources have been sought after as critical components of quantum information science. We report an efficient and tunable single photon source based on an InAs quantum dot (QD) ...
  • Efficient slow-light coupling in a photonic crystal waveguide without transition region 

    White, T. P.; Botten, L. C.; de Sterke, C. Martijn; Dossou, K. B.; McPhedran, R. C. (2008-11-15) - Journal article
    We consider the coupling into a slow mode that appears near an inflection point in the band structure of a photonic crystal waveguide. Remarkably, the coupling into this slow mode, which has a group index n(g) > 1000, can ...
  • Efficient synthesis of novel chalcogen-containing derivatives of DNA nucleobases 

    Hua, Guoxiong; Du, Junyi; Cordes, David Bradford; Slawin, Alexandra Martha Zoya; Woollins, J Derek (2015-03-25) - Journal article
    The formation of a library of chalcogen-containing DNA nucleobase derivatives is presented. Reacting easily accessible 9-(2-bromoethyl)adenine with chalcogen-containing nucleophilic reagents led to a series of novel ...
  • Eggshell appearance does not signal maternal corticosterone exposure in japanese quail : an experimental study with brown-spotted eggs 

    Duval, Camille; Cassey, Phillip; Lovell, Paul G.; Miksik, Ivan; Reynolds, S. James; Spencer, Karen A. (2013-12-03) - Journal article
    Reproduction is a critical period for birds as they have to cope with many stressful events. One consequence of an acute exposure to stress is the release of corticosterone, the avian stress hormone. Prolonged stress can ...
  • EL CVn-type binaries - discovery of 17 helium white dwarf precursors in bright eclipsing binary star systems 

    Maxted, P. F. L.; Bloemen, S.; Heber, U.; Geier, S.; Wheatley, P. J.; Marsh, T. R.; Breedt, E.; Sebastian, D.; Faillace, G.; Owen, C.; Pulley, D.; Smith, D.; Kolb, U.; Haswell, C. A.; Southworth, J.; Anderson, D. R.; Smalley, B.; Cameron, A. Collier; Hebb, L.; Simpson, E. K.; West, R. G.; Bochinski, J.; Busuttil, R.; Hadigal, S. (2014-01-11) - Journal article
    The star 1SWASP J024743.37-251549.2 was recently discovered to be a binary star in which an A-type dwarf star eclipses the remnant of a disrupted red giant star (WASP 0247-25 B). The remnant is in a rarely observed state ...
  • El exilio en la poesía de Tomás Segovia y Angelina Muñiz Huberman 

    Tasis Moratinos, Eduardo (University of St Andrews, 2011-05-23) - Thesis
    Tomás Segovia and Angelina Muñiz Huberman belong to a group of writers known as «Hispanomexicanos». Most approaches to this generation have been towards the role that exile plays in their early work, paying almost no ...
  • El final de El astillero 

    San Román, Gustavo (2003) - Journal article
    The novel El astillero (Buenos Aires 1961), by Juan Carlos Onetti, provides two alternative endings, which have inspired a number of interpretations. The present article provides a reading based on the tension in the novel ...
  • El pronunciamiento mexicano del siglo XIX : Hacia una nueva tipología 

    Fowler, Will (2009-07) - Journal article
    Tras la guerra de Independencia (1810-1821) estallaron más de 1 500 pronunciamientos entre el Plan de Iguala de 1821 y el Plan de Tuxtepec de 1876. En varios casos degeneraron en enfrentamientos de una violencia atroz como ...
  • Elaborator reflection : extending Idris in Idris 

    Christiansen, David; Brady, Edwin Charles (ACM Press - Association for Computing Machinery, 2016-09-04) - Conference item
    Many programming languages and proof assistants are defined by elaboration from a high-level language with a great deal of implicit information to a highly explicit core language. In many advanced languages, these elaboration ...
  • Elastic and magnetoelastic relaxation behaviour of multiferroic (ferromagnetic + ferroelectric + ferroelastic) Pb(Fe0.5Nb0.5)O3 perovskite 

    Carpenter, M. A.; Schiemer, J. A.; Lascu, I.; Harrison, R. J.; Kumar, A.; Katiyar, R. S.; Ortega, N.; Sanchez, D. A.; Mejia, C. Salazar; Schnelle, W.; Echizen, M.; Shinohara, H.; Heap, A. J. F.; Nagaratnam, R.; Dutton, S. E.; Scott, James Floyd (2015-06-30) - Journal article
    Resonant Ultrasound Spectroscopy has been used to characterize elastic and anelastic anomalies in a polycrystalline sample of multiferroic Pb(Fe0.5Nb0.5)O3 (PFN). Elastic softening begins at ~550 K, which is close to the ...
  • Elastic selves and fluid cosmologies : Nahua resilience in a changing world 

    Feather, Conrad (University of St Andrews, 2010-11) - Thesis
    In May 1984, the Nahua, a Panoan speaking indigenous people living in a remote corner of the Peruvian Amazon, experienced their ‘first contact’ with Peruvian national society. 25 years later they appear to many observers ...