Now showing items 1774-1793 of 8185

  • Discovery and observations of ASASSN-13db, an EX lupi-type accretion event on a low-mass T tauri star 

    Holoien, T.W.-S.; Prieto, J.L.; Stanek, K.Z.; Kochanek, C.S.; Shappee, B.J.; Zhu, Z.; Sicilia-Aguilar, A.; Grupe, D.; Croxall, K.; Adams, J.J.; Simon, J.D.; Morrell, N.; McGraw, S.M.; Wagner, R.M.; Basu, U.; Beacom, J.F.; Bersier, D.; Brimacombe, J.; Jencson, J.; Pojmanski, G.; Starrfield, S.G.; Szczygieł, D.M.; Woodward, C.E. (2014-04-20) - Journal article
    We discuss ASASSN-13db, an EX Lupi-type ("EXor") accretion event on the young stellar object (YSO) SDSS J051011.01-032826.2 (hereafter SDSSJ0510) discovered by the All-Sky Automated Survey for SuperNovae (ASAS-SN). Using ...
  • Discovery and validation of SIRT2 inhibitors based on tenovin-6 : use of a 1H-NMR method to assess deacetylase activity 

    Pirrie, Lisa; McCarthy, Anna R.; Major, Louise L.; Morkunaite, Vaida; Zubriene, Asta; Matulis, Daumantas; Lain, Sonia; Lebl, Tomas; Westwood, Nicholas J. (2012-10) - Journal article
    The search for potent and selective sirtuin inhibitors continues as chemical tools of this type are of use in helping to assign the function of this interesting class of deacetylases. Here we describe SAR studies starting ...
  • Discovery of a novel ligand that modulates the protein-protein interactions of the AAA+ superfamily oncoprotein reptin 

    Healy, Alan; Houston, Douglas R.; Remnant, Lucy; Huart, Anne-Sophie; Brychtova, Veronika; Maslon, Magda M.; Meers, Olivia; Muller, Petr; Krecji, Adam; Blackburn, Elizabeth M.; Vojtesek, B.; Hernychova, Lenka; Walkinshaw, M. D.; Westwood, Nicholas James; Hupp, Ted (2015) - Journal article
    Developing approaches to discover protein-protein interactions (PPIs) remains a fundamental challenge. A chemical biology platform is applied here to identify novel PPIs for the AAA+ superfamily oncoprotein reptin. An in ...
  • Discovery of a visual T-dwarf triple system and binarity at the L/T transition 

    Radigan, Jacqueline; Jayawardhana, Ray; Lafrenière, David; Dupuy, Trent J.; Liu, Michael C.; Scholz, Alexander (2013-11-20) - Journal article
    We present new high contrast imaging of eight L/T transition brown dwarfs (BDs) using the NIRC2 camera on the Keck II telescope. One of our targets, the T3.5 dwarf 2MASS J08381155+1511155, was resolved into a hierarchal ...
  • Discovery of intramolecular trans-sialidases in human gut microbiota suggests novel mechanisms of mucosal adaptation 

    Tailford, Louise E.; Owen, C. David; Walshaw, John; Crost, Emmanuelle H.; Hardy-Goddard, Jemma; Le Gall, Gwenaelle; de Vos, Willem M.; Taylor, Garry L.; Juge, Nathalie (2015-07) - Journal article
    The gastrointestinal mucus layer is colonized by a dense community of microbes catabolizing dietary and host carbohydrates during their expansion in the gut. Alterations in mucosal carbohydrate availability impact on the ...
  • The discovery of new deep-sea hydrothermal vent communities in the southern ocean and implications for biogeography 

    Rogers, Alex D.; Tyler, Paul A.; Connelly, Douglas P.; Copley, Jon T.; James, Rachael; Larter, Robert D.; Linse, Katrin; Mills, Rachel A.; Garabato, Alfredo Naveira; Pancost, Richard D.; Pearce, David A.; Polunin, Nicholas V. C.; German, Christopher R.; Shank, Timothy; Boersch-Supan, Philipp H.; Alker, Belinda J.; Aquilina, Alfred; Bennett, Sarah A.; Clarke, Andrew; Dinley, Robert J. J.; Graham, Alastair G. C.; Green, Darryl R. H.; Hawkes, Jeffrey A.; Hepburn, Laura; Hilario, Ana; Huvenne, Veerle A. I.; Marsh, Leigh; Ramirez-Llodra, Eva; Reid, William D. K.; Roterman, Christopher N.; Sweeting, Christopher J.; Thatje, Sven; Zwirglmaier, Katrin (2012-01) - Journal article
    Since the first discovery of deep-sea hydrothermal vents along the Galapagos Rift in 1977, numerous vent sites and endemic faunal assemblages have been found along mid-ocean ridges and back-arc basins at low to mid latitudes. ...
  • Discovery of the Fomalhaut C debris disc 

    Kennedy, G.M.; Wyatt, M.C.; Kalas, P.; Duchêne, G.; Sibthorpe, B.; Lestrade, J.-F.; Matthews, B.C.; Greaves, J. (2014-02-11) - Journal article
    Fomalhaut is one of the most interesting and well-studied nearby stars, hosting at least one planet, a spectacular debris ring and two distant low-mass stellar companions (TW PsA and LP 876-10, a.k.a. Fomalhaut B and C). ...
  • Discovery of WASP-65b and WASP-75b : two hot Jupiters without highly inflated radii 

    Gómez Maqueo Chew, Y.; Faedi, F.; Pollacco, D.; Brown, David John Alexander; Doyle, A.P.; Collier Cameron, A.; Gillon, M.; Lendl, M.; Smalley, B.; Triaud, A.H.M.J.; West, R.G.; Wheatley, P.J.; Busuttil, R.; Liebig, C.; Anderson, D.R.; Armstrong, D.J.; Barros, S.C.C.; Bento, J.; Bochinski, J.; Burwitz, V.; Delrez, L.; Enoch, B.; Fumel, A.; Haswell, C.A.; Hébrard, G.; Hellier, C.; Holmes, S.; Jehin, E.; Kolb, U.; Maxted, P.F.L.; McCormac, J.; Miller, G.R.M.; Norton, A.J.; Pepe, F.; Queloz, D.; Rodríguez, J.; Ségransan, D.; Skillen, I.; Stassun, K.G.; Udry, S.; Watson, C. (2013-11-01) - Journal article
    We report the discovery of two transiting hot Jupiters, WASP-65b (Mpl = 1.55 ± 0.16 MJ; Rpl = 1.11 ± 0.06 RJ), and WASP-75b (Mpl = 1.07 ± 0.05 MJ; Rpl = 1.27 ± 0.05 RJ). They orbit their host star every ~2.311, and ~2.484 ...
  • Discovery theology: reflecting people by the Tay 

    Gammack, George (St Mary's College, University of St Andrews, 2006-06-01) - Journal article
    George Gammack’s paper emerges from the context of his ministry in the Whitfield area of Dundee. He describes a parish marked by significant levels of deprivation and seeks ways in which to forge a theology relevant to ...
  • Discovery, in vivo activity, and mechanism of action of a small-molecule p53 activator 

    Lain, Sonia; Hollick, Jonathan J.; Campbell, Johanna; Staples, Oliver D.; Higgins, Maureen; Aoubala, Mustapha; McCarthy, Anna; Appleyard, Virginia; Murray, Karen E.; Baker, Lee; Thompson, Alastair; Mathers, Joanne; Holland, Stephen J.; Stark, Michael J. R.; Pass, Georgia; Woods, Julie; Lane, David P.; Westwood, Nicholas J. (2008-05-06) - Journal article
    We have carried out a cell-based screen aimed at discovering small molecules that activate p53 and have the potential to decrease tumor growth. Here, we describe one of our hit compounds, tenovin-1, along with a more ...
  • Discrepancies between isochrone fitting and gyrochronology for exoplanet host stars? 

    Brown, D.J.A. (2014-08-01) - Journal article
    Using a sample of 68 planet-hosting stars, I carry out a comparison of isochrone fitting and gyrochronology to investigate whether tidal interactions between the stars and their planets are leading to underestimated ages ...
  • Discrimination of fast click series produced by tagged Risso’s dolphins (Grampus griseus) for echolocation or communication 

    Arranz Alonso, P.; DeRuiter, S. L.; Stimpert, A. K.; Neves, Silvana; Friedlaender, A. S.; Goldbogen, J. A.; Visser, F.; Calambokidis, J.; Southall, B. L.; Tyack, P. L. (2016-07-08) - Journal article
    Early studies that categorized odontocete pulsed sounds had few means of discriminating signals used for biosonar-based foraging from those used for communication. This capability to identify the function of sounds is ...
  • A discussion of pneumatology and the linguistic turn to practice, with reference to Kevin Vanhoozer’s canonical-linguistic approach to Christian theology 

    Bellenger, Peter John Russell (University of St Andrews, 2009-11-30) - Thesis
    This dissertation assesses the pneumatological implications of Kevin Vanhoozer’s canonical-linguistic approach to Christian theology, in the context of the wider issue of recent interest in re-conceiving the cultural-linguistic ...
  • Disease progression in Plasmodium knowlesi malaria is linked to variation in invasion gene family members 

    Ahmed, Atique M.; Monsanto Pinheiro, Miguel; Divis, Paul C.; Siner, Angela; Zainudin, Ramlah; Wong, Ing Tien; Lu, Chan Woon; Singh-Khaira, Sarina K.; Millar, Scott B.; Lynch, Sean; Willmann, Matthias; Singh, Balbir; Krishna, Sanjeev; Cox Singh, Janet (2014-08-14) - Journal article
    Plasmodium knowlesi, a parasite of Southeast Asian macaques, has entered the human population. Approximately 10% of P. knowlesi infections are severe, 1–2% are fatal, in Sarawak, Malaysian Borneo. Increase in parasitaemia ...
  • Disentangling planetary orbits from stellar activity in radial-velocity surveys 

    Haywood, R.D.; Cameron, A.C.; Queloz, D.; Barros, S.C.C.; Deleuil, M.; Fares, R.; Gillon, M.; Hatzes, A.; Lanza, A.F.; Lovis, C.; Moutou, C.; Pepe, F.; Pollacco, D.; Santerne, A.; Ségransan, D.; Unruh, Y. (2014-04-01) - Journal article
    The majority of extra-solar planets have been discovered (or confirmed after follow-up) through radial-velocity (RV) surveys. Using ground-based spectrographs such as High Accuracy Radial Velocity Planetary Search (HARPS) ...
  • Disinflation and exchange-rate pass-through 

    Senay, Ozge (2008-04) - Journal article
    This paper analyzes exchange-rate dynamics following a money-based disinflation under different degrees of exchange-rate pass-through. Using a microfounded dynamic general equilibrium model with imperfect competition and ...
  • The disk around the brown dwarf KPNO TAU 3 

    Broekhoven-Fiene, H.; Matthews, B.; Duchêne, G.; Di Francesco, J.; Scholz, A.; Chrysostomou, A.; Jayawardhana, R. (2014-07-10) - Journal article
    We present submillimeter observations of the young brown dwarfs KPNO Tau 1, KPNO Tau 3, and KPNO Tau 6 at 450 μm and 850 μm taken with the Submillimetre Common-User Bolometer Array on the James Clerk Maxwell Telescope. ...
  • Disk evolution, element abundances and cloud properties of young gas giant planets 

    Helling, C.; Woitke, P.; Rimmer, P.B.; Kamp, I.; Thi, W.-F.; Meijerink, R. (2014-04-14) - Journal article
    We discuss the chemical pre-conditions for planet formation, in terms of gas and ice abundances in a protoplanetary disk, as function of time and position, and the resulting chemical composition and cloud properties in the ...
  • Dislocation and relocation: clarsach and live electronics 

    MacDonald, Alistair (The Royal Conservatoire of Scotland, 2014-12-16) - Journal article
    In writing The Salutation (clarsach and electroacoustic sound) for harpist Catriona McKay in 2002, I wanted to create something which celebrated the history and music of the instrument itself, using studio technology to ...
  • Dismissivism in metaphysics : debates about what there is and debates about what grounds what 

    Porro, Laura Cecilia (University of St Andrews, 2013-11-30) - Thesis
    In this thesis I focus on dismissivism in metaphysics. Some philosophers argue that at least some metaphysical disputes are not substantial, and as a consequence should be dismissed. In this work I restrict my attention ...