Now showing items 1771-1790 of 9424

  • Deep sequencing analysis of defective genomes of parainfluenza virus 5 and their role in interferon induction 

    Killip, M. J.; Young, D. F.; Gatherer, D.; Ross, C. S.; Short, J. A. L.; Davison, A. J.; Goodbourn, S.; Randall, R. E. (2013-05) - Journal article
    Preparations of parainfluenza virus 5 (PIV5) that are potent activators of the interferon (IFN) induction cascade were generated by high-multiplicity passage in order to accumulate defective interfering virus genomes (DIs). ...
  • Deep spectroscopic luminosity function of Abell 85 : no evidence for a steep upturn of the faint-end slope 

    Agulli, I.; Aguerri, J. A. L.; Sanchez-Janssen, R.; Barrena, R.; Diaferio, A.; Serra, A. L.; Mendez Abreu, Jairo (2014-10-11) - Journal article
    We present a new deep determination of the spectroscopic luminosity function (LF) within the virial radius of the nearby and massive Abell 85 (A85) cluster down to the dwarf regime (M* + 6) using Very Large Telescope/Visible ...
  • Deep water formation in the North Pacific and deglacial CO2 rise 

    Rae, James William Buchanan; Sarnthein, Michael; Foster, Gavin; Ridgwell, Andy; Grootes, Pieter; Elliott, Tim (2014-06) - Journal article
    Deepwater formation in the North Atlantic and Southern Ocean is widely thought to influence deglacial CO2 rise and climate change; here we suggest that deep water formation in the North Pacific may also play an important ...
  • Deep-brain photoreception links luminance detection to motor output in Xenopus frog tadpoles 

    Currie, Stephen Paul; Doherty, Gayle Helane; Sillar, Keith Thomas (2016-05-10) - Journal article
    Non-visual photoreceptors are widely distributed in the retina and brain but their roles in animal behaviour remain poorly understood. Here we document a novel form of deep-brain photoreception in Xenopus laevis frog ...
  • The DeepMIP contribution to PMIP4 : experimental design for model simulations of the EECO, PETM, and pre-PETM (version 1.0) 

    Lunt, Daniel J.; Huber, Matthew; Anagnostou, Eleni; Baatsen, Michiel L. J.; Caballero, Rodrigo; DeConto, Rob; Dijkstra, Henk A.; Donnadieu, Yannick; Evans, David; Feng, Ran; Foster, Gavin L.; Gasson, Ed; Von Der Heydt, Anna S.; Hollis, Chris J.; Inglis, Gordon N.; Jones, Stephen M.; Kiehl, Jeff; Turner, Sandy Kirtland; Korty, Robert L.; Kozdon, Reinhardt; Krishnan, Srinath; Ladant, Jean Baptiste; Langebroek, Petra; Lear, Caroline H.; LeGrande, Allegra N.; Littler, Kate; Markwick, Paul; Otto-Bliesner, Bette; Pearson, Paul; Poulsen, Christopher J.; Salzmann, Ulrich; Shields, Christine; Snell, Kathryn; Stärz, Michael; Super, James; Tabor, Clay; Tierney, Jessica E.; Tourte, Gregory J. L.; Tripati, Aradhna; Upchurch, Garland R.; Wade, Bridget S.; Wing, Scott L.; Winguth, Arne M. E.; Wright, Nicky M.; Zachos, James C.; Zeebe, Richard E. (2017-02-23) - Journal article
    Past warm periods provide an opportunity to evaluate climate models under extreme forcing scenarios, in particular high (> 800ppmv) atmospheric CO2 concentrations. Although a post hoc intercomparison of Eocene (∼ 50 Ma) ...
  • The Deepwater Horizon oil spill marine mammal injury assessment 

    Takeshita, Ryan; Sullivan, Laurie; Smith, Cynthia; Collier, Tracy; Hall, Ailsa; Brosnan, Tom; Rowles, Teri; Schwacke, Lori (2017-01-31) - Journal item
    From 2010 to 2015, a team of scientists studied how the BP Deepwater Horizon (DWH) oil spill affected marine mammals inhabiting the northern Gulf of Mexico, as part of the DWH Natural Resource Damage Assessment process. ...
  • DEER sensitivity between iron centers and nitroxides in heme-containing proteins improves dramatically using broadband, high-field EPR 

    Motion, Claire Louise; Lovett, Janet Eleanor; Bell, Stacey; Cassidy, Scott Lindsay; Cruickshank, Paul Alexander Sawchuk; Bolton, David Robert; Hunter, Robert Iain; El Mkami, Hassane; Van Doorslaer, Sabine; Smith, Graham Murray (2016-04) - Journal article
    This work demonstrates the feasibility of making sensitive nanometer distance measurements between Fe(III) heme centers and nitroxide spin labels in proteins using the double electron-electron resonance (DEER) pulsed EPR ...
  • A default prior distribution for contingency tables with dependent factor levels 

    Overstall, Antony; King, Ruth (2014-01) - Journal article
    A default prior distribution is proposed for the Bayesian analysis of contingency tables. The prior is specified to allow for dependence between levels of the factors. Different dependence structures are considered, including ...
  • Defeating pragmatic encroachment? 

    McGrath, Matthew (2016-11-15) - Journal article
    This paper examines the prospects of a prima facie attractive response to Fantl and McGrath's argument for pragmatic encroachment. The response concedes that if one knows a proposition to be true then that proposition is ...
  • Defective interfering particles of parainfluenza virus subtype 5 and interferon induction 

    Short, John A. L. (University of St Andrews, 2015) - Thesis
    The innate immune response is the first line of defence against virus infection. Cells contain a diverse array of pathogen recognition receptors (PRRs) that are able to recognise multiple pathogen associated molecular ...
  • Defects in sodalite-group minerals determined from X-ray-induced luminescence 

    Finch, Adrian Anthony; Mortensen, Henrik Friis; Maghrabi, Mufeed (2016-07) - Journal article
    The luminescence spectra of a suite of natural sodium framework silicates including four different sodalite variants and tugtupite have been collected during X-ray irradiation as a function of temperature between 20 and ...
  • A defence of the Kaplanian theory of sentence truth 

    Sweeney, Paula (University of St Andrews, 2010-06) - Thesis
    When David Kaplan put forward his theory of sentence truth incorporating demonstratives, initially proposed in ‘Dthat’ (1978) and later developed in ‘Demonstratives’ (1989a) and ‘Afterthoughts’ (1989b), it was, to his ...
  • Defending the “Satanic Verses” : constructive engagement: British-Iranian relations and the right to freedom of expression (1989-2004) 

    Kaussler, Bernd (University of St Andrews, 2008) - Thesis
    This thesis aims to conceptualize what is often referred to in diplomacy, as a policy of “constructive engagement”, by employing neoliberal-institutionalist theories and conflict resolution approaches. The adopted “model ...
  • 'Defensive liberal wars' : the global war on terror and the return of illiberalism in American foreign policy 

    Singh, R. (2015-03) - Journal article
    This paper offers an analysis of the illiberal practices and discourse of the Global War on Terror (GWoT) and demonstrates how the United States of America used the liberal argument as a qualitative metric of its success ...
  • Deficiency of G1 regulators P53, P21Cip1 and/or pRb decreases hepatocyte sensitivity to TGFbeta cell cycle arrest 

    Sheahan, Sharon; Bellamy, Christopher O; Dunbar, Donald R; Harrison, David J; Prost, Sandrine (2007-11-19) - Journal article
    TGFbeta is critical to control hepatocyte proliferation by inducing G1-growth arrest through multiple pathways leading to inhibition of E2F transcription activity. The retinoblastoma protein pRb is a key controller of E2F ...
  • Deficits in facial, body movement and vocal emotional processing in autism spectrum disorders 

    Philip, R. C. M.; Whalley, H. C.; Stanfield, A. C.; Sprengelmeyer, Reiner Heinrich; Santos, I. M.; Young, A. W.; Atkinson, A. P.; Calder, A. J.; Johnstone, E. C.; Lawrie, S. M.; Hall, J. (2010-11) - Journal article
    Background. Previous behavioural and neuroimaging studies of emotion processing in autistic spectrum disorder (ASD) have focused on the use of facial stimuli. To date, however, no studies have examined emotion processing ...
  • Defining a role for the peduncolopontine tegmental nucleus in striatal outflow 

    Allen, Laura F. (University of St Andrews, 1996) - Thesis
    The pedunculopontine tegmental nucleus (PPTg) lies within the pontomesencephalon and contains cholinergic and non-cholinergic neurones. It has extensive afferent and efferent connections throughout the brain. Early ...
  • Defining and evaluating the impact of cross-disciplinary conservation research 

    Evely, Anna C.; Fazey, Ioan; Lambin, Xavier; Lambert, Emily; Allen, Sarah; Pinard, Michelle (2010-12) - Journal article
    Cross-disciplinary research is advocated as a way of improving understanding of the complexity of environmental problems; cross-disciplinary projects, centres and academic institutes have increased. However, there is ...
  • Defining art culturally : modern theories of art - a synthesis 

    Fokt, Simon (University of St Andrews, 2013-06-27) - Thesis
    Numerous theories have attempted to overcome the anti-essentialist scepticism about the possibility of defining art. While significant advances have been made in this field, it seems that most modern definitions fail to ...
  • Defining terrorism at the Special Tribunal for Lebanon 

    Puchooa, Prakash (Centre for the Study of Terrorism and Political Violence, University of St Andrews, 2011-11-11) - Journal article
    On 16 February 2011, the Appeals Chamber of the Special Tribunal for Lebanon (STL) issued an interlocutory decision regarding the legal definition of terrorism.This decision was in response to a Pre-Trial Chamber (PTC) ...