Now showing items 1053-1072 of 11957

  • C9ORF72 repeat expansion causes vulnerability of motor neurons to Ca2+-permeable AMPA receptor-mediated excitotoxicity 

    Thangaraj Selvaraj, Bhuvaneish; Livesey, Matthew; Zhao, Chen; Gregory, Jenna; James, Owain; Cleary, Elaine; Chouhan, Amit Kumar; Gane, Angus; Perkins, Emma; Dando, Owen; Lillico, Simon; Lee, Youn-Bok; Nishimura, Agnes; Poreci, Urjana; Thankamony, Sai; Pray, Meryll; Vasistha, Navneet; Magnani, Dario; Borooah, Shyamanga; Burr, Karen; Story, David; McCampbell, Alexander; Shaw, Christopher; Kind, Peter; Aitman, Timothy J.; Whitelaw, Bruce; Wilmut, Ian; Smith, Colin; Miles, Gareth B.; Hardingham, Giles; Wyllie, David; Chandran, Siddharthan (2018-01-24) - Journal article
    Mutations in C9ORF72 are the most common cause of familial amyotrophic lateral sclerosis (ALS). Here, through a combination of RNA-seq and electrophysiological studies on induced pluripotent stem cell (iPSC) derived motor ...
  • The Ca2+ sensor protein Swiprosin-1/EFhd2 is present in neurites and involved in kinesin-mediated transport in neurons 

    Purohit, P; Perez-Branguli, F; Prots, I; Borger, Eva; Gunn-Moore, Frank J; Welzel, O; Loy, K; Wenzel, EM; Gromer, TW; Brachs, S; Holzer, M; Buslei, R; Fritsch, K; Regensburger, M; Bohm, KJ; Winner, B; Mielenz, D (2014-08-18) - Journal article
    Swiprosin-1/EFhd2 (EFhd2) is a cytoskeletal Ca2+ sensor protein strongly expressed in the brain. It has been shown to interact with mutant tau, which can promote neurodegeneration, but nothing is known about the physiological ...
  • Caccheo y Minería Mediana en las Provincias de Potosí : Lípez y Porco (1830-1850) 

    Platt, Tristan (2014-11) - Journal article
    The article examines small and medium silver mining in two provinces of Potosí (Bolivia) during the early Republic, situating it between state buying, minting policies and smuggling via the "silver road" to Salta and the ...
  • The Cajal body and the nucleolus : “in a relationship” or “it's complicated”? 

    Trinkle-Mulcahy, Laura; Sleeman, Judith E. (2017) - Journal item
    From their initial identification as 'nucleolar accessory bodies' more than a century ago, the relationship between Cajal bodies and nucleoli has been a subject of interest and controversy. In this review, we seek to place ...
  • Calcisponges have a ParaHox gene and dynamic expression of dispersed NK homeobox genes 

    Fortunato, Sofia; Adamski, Marcin; Mendivil Ramos, Olivia; Leininger, Sven; Liu, Jing; Ferrier, David Ellard Keith; Adamska, Maja (2014-10-30) - Journal article
    Sponges are simple animals with few cell types, but their genomes paradoxically contain a wide variety of developmental transcription factors1–4, including homeobox genes belonging to the Antennapedia (ANTP) class5,6, which ...
  • Calcium ions alter monoamine oxidase A activity 

    Ramsay, Rona R.; Armstrong, Stephanie (Lulu, 2013) - Conference item
    Activation of the flavoprotein monoamine oxidase A (MAO A) by calcium ions has been reported in isolated mitochondria, in cell lines, and in vivo. Enhanced MAO A activity has been associated with a rise in oxidative damage ...
  • Calcium manganite as oxygen electrode materials for reversible solid oxide fuel cell 

    Ni, Chengsheng; Irvine, John T.S. (2015) - Journal article
    For an efficient high-temperature reversible solid oxide fuel cell (RSOFC), the oxygen electrode should be highly active for the conversion between oxygen anions and oxygen gas. CaMnO3-δ(CM) is a perovskite that can be ...
  • The calcium-binding protein EFhd2 modulates synapse formation in vitro and Is linked to human dementia 

    Borger, Eva; Herrmann, Abigail; Mann, David; Spires-Jones, Tara; Gunn-Moore, Frank J (2014-10) - Journal article
    EFhd2 is a calcium-binding adaptor protein that has been found to be associated with pathologically aggregated tau in the brain in Alzheimer disease and in a mouse model of frontotemporal dementia. EFhd2 has cell type–specific ...
  • Calculating NMR parameters in aluminophosphates : evaluation of dispersion correction schemes 

    Sneddon, Scott; Dawson, Daniel M.; Pickard, Chris J.; Ashbrook, Sharon E. (2014-02) - Journal article
    Periodic density functional theory (DFT) calculations have recently emerged as a popular tool for assigning solid-state nuclear magnetic resonance (NMR) spectra. However, in order for the calculations to yield accurate ...
  • Calculating Time and the End of Time in the Carolingian World, c.740-820 

    Palmer, James Trevor (2011-12) - Journal article
    The hopes and fears associated with the imminence of apocalypse acted as catalysts for a number of significant changes in history. Relevant patterns of behaviour are not, however, always consistent. This paper examines the ...
  • Calculation of a standard reformed biogas composition and testing on SOFC anode powders 

    Gamble, Stephen Richard; Neagu, Dragos; Irvine, John Thomas Sirr (Electrochemical Society, 2013) - Conference item
    A standard reformed biogas composition, based on a 63% CH4 37% CO2 input biogas, was defined by calculation. It is designed to resemble the composition of biogas that would enter a real SOFC stack, assuming 80% fuel ...
  • Calculation of the emission power distribution of microstructured OLEDs using the reciprocity theorem 

    Zhang, S.; Martins, E.R.; Diyaf, A.G.; Wilson, J.I.B.; Turnbull, G.A.; Samuel, Ifor David William (2015-07) - Journal article
    Integrating photonic microstructures into organic light-emitting diodes (OLEDs) has been a widely used strategy to improve their light out-coupling efficiency. However, there is still a need for optical modelling methods ...
  • Calculations of One-Electron Redox Potentials of Oxoiron(IV) Porphyrin Complexes 

    Castro, Ludovic; Buehl, Michael (2014-01) - Journal article
    Density functional theory calculations have been performed to calculate the one-electron redox potential for a series of oxoiron(IV) porphyrin complexes of the form [(TMP)Fe-IV(O)(L)] (TMP = 5,10,15,20-tetramesitylporphyrinate). ...
  • A Calendar of Happenings : Allan Kaprow, counter-chronologies and cataloguing performance, c. 1970 

    Spencer, Catherine Elizabeth (2016-06-01) - Journal article
  • Calibrating animal-borne proximity loggers 

    Rutz, Christian; Morrissey, Michael Blair; Burns, Zackory; Burt, John; Otis, Brian; St Clair, James; James, Richard (2015-06) - Journal article
    1. Growing interest in the structure and dynamics of animal social networks has stimulated efforts to develop automated tracking technologies that can reliably record encounters in free-ranging subjects. A particularly ...
  • Calibration of the B/Ca proxy in the planktic foraminifer Orbulina universa to Paleocene seawater conditions 

    Haynes, Laura L.; Hönisch, Bärbel; Dyez, Kelsey A.; Holland, Kate; Rosenthal, Yair; Fish, Carina R.; Subhas, Adam V.; Rae, James W. B. (2017-06) - Journal article
    The B/Ca ratio of planktic foraminiferal calcite, a proxy for the surface ocean carbonate system, displays large negative excursions during the Paleocene-Eocene Thermal Maximum (PETM, 55.9 Ma), consistent with rapid ocean ...
  • Calibration of the chaotic interest rate model 

    Tsujimoto, Tsunehiro (University of St Andrews, 2010-11-30) - Thesis
    In this thesis we establish a relationship between the Potential Approach to interest rates and the Market Models. This relationship allows us to derive the dynamics of forward LIBOR rates and forward swap rates by modelling ...
  • Calibration of the torsional and lateral spring constants of cantilever sensors 

    Parkin, John David; Hähner, Georg (2014-06-06) - Journal article
    A method suitable for the calibration of the spring constants of all torsional and lateral eigenmodes of micro- and nanocantilever sensors is described. Such sensors enable nanomechanical measurements and the characterization ...
  • CALIFA : a diameter-selected sample for an integral field spectroscopy galaxy survey 

    Walcher, C. J.; Wisotzki, L.; Bekeraite, S.; Husemann, B.; Iglesias-Paramo, J.; Backsmann, N.; Barrera Ballesteros, J.; Catalan-Torrecilla, C.; Cortijo, C.; del Olmo, A.; Garcia Lorenzo, B.; Falcon-Barroso, J.; Jilkova, L.; Kalinova, V.; Mast, D.; Marino, R. A.; Mendez Abreu, Jairo; Pasquali, A.; Sanchez, S. F.; Trager, S.; Zibetti, S.; Aguerri, J. A. L.; Alves, J.; Bland-Hawthorn, J.; Boselli, A.; Castillo Morales, A.; Cid Fernandes, R.; Flores, H.; Galbany, L.; Gallazzi, A.; Garcia-Benito, R.; Gil de Paz, A.; Gonzalez-Delgado, R. M.; Jahnke, K.; Jungwiert, B.; Kehrig, C.; Lyubenova, M.; Marquez Perez, I.; Masegosa, J.; Ibero, A. Monreal; Perez, E.; Quirrenbach, A.; Rosales-Ortega, F. F.; Roth, M. M.; Sanchez-Blazquez, P.; Spekkens, K.; Tundo, E.; van de Ven, G.; Verheijen, M. A. W.; Vilchez, J. V.; Ziegler, B. (2014-09) - Journal article
    We describe and discuss the selection procedure and statistical properties of the galaxy sample used by the Calar Alto Legacy Integral Field Area (CALIFA) survey, a public legacy survey of 600 galaxies using integral field ...
  • CALIFA, the Calar Alto Legacy Integral Field Area survey : II. First public data release 

    Husemann, B.; Jahnke, K.; Sanchez, S. F.; Barrado, D.; Bekeraite, S.; Bomans, D. J.; Castillo-Morales, A.; Catalan-Torrecilla, C.; Cid Fernandes, R.; Falcon-Barroso, J.; Garcia-Benito, R.; Gonzalez Delgado, R. M.; Iglesias-Paramo, J.; Johnson, B. D.; Kupko, D.; Lopez-Fernandez, R.; Lyubenova, M.; Marino, R. A.; Mast, D.; Miskolczi, A.; Monreal-Ibero, A.; Gil de Paz, A.; Perez, E.; Perez, I.; Rosales-Ortega, F. F.; Ruiz-Lara, T.; Schilling, U.; van de Ven, G.; Walcher, J.; Alves, J.; de Amorim, A. L.; Backsmann, N.; Barrera-Ballesteros, J. K.; Bland-Hawthorn, J.; Cortijo, C.; Dettmar, R. -J.; Demleitner, M.; Diaz, A. I.; Enke, H.; Florido, E.; Flores, H.; Galbany, L.; Gallazzi, A.; Garcia-Lorenzo, B.; Gomes, J. M.; Gruel, N.; Haines, T.; Holmes, L.; Jungwiert, B.; Kalinova, V.; Kehrig, C.; Kennicutt, R. C.; Klar, J.; Lehnert, M. D.; Lopez-Sanchez, A. R.; de Lorenzo-Caceres, A.; Marmol-Queralto, E.; Marquez, I.; Mendez-Abreu, J.; Molla, M.; del Olmo, A.; Meidt, S. E.; Papaderos, P.; Puschnig, J.; Quirrenbach, A.; Roth, M. M.; Sanchez-Blazquez, P.; Spekkens, K.; Singh, R.; Stanishev, V.; Trager, S. C.; Vilchez, J. M.; Wild, V.; Wisotzki, L.; Zibetti, S.; Ziegler, B. (2013-01) - Journal article
    We present the first public data release (DR1) of the Calar Alto Legacy Integral Field Area (CALIFA) survey. It consists of science-grade optical datacubes for the first 100 of eventually 600 nearby (0.005 < z < 0.03) ...