Now showing items 1-9 of 9

    • Burkholderia pseudomallei genome plasticity associated with genomic island variation 

      Tumapa, Sarinna; Holden, Matthew T. G.; Vesaratchavest, Mongkol; Wuthiekanun, Vanaporn; Limmathurotsakul, Direk; Chierakul, Wirongrong; Feil, Edward J.; Currie, Bart J.; Day, Nicholas P. J.; Nierman, William C.; Peacock, Sharon J. (2008-04-25) - Journal article
      Background: Burkholderia pseudomallei is a soil-dwelling saprophyte and the cause of melioidosis. Horizontal gene transfer contributes to the genetic diversity of this pathogen and may be an important determinant of virulence ...
    • The genome of the yellow potato cyst nematode, Globodera rostochiensis, reveals insights into the basis of parasitism and virulence 

      Eves-van den Akker, Sebastian; Laetsch, Dominik R.; Thorpe, Peter; Lilley, Catherine J.; Danchin, Etienne G. J.; Da Rocha, Martine; Rancurel, Corinne; Holroyd, Nancy E.; Cotton, James A.; Szitenberg, Amir; Grenier, Eric; Montarry, Josselin; Mimee, Benjamin; Duceppe, Marc-Olivier; Boyes, Ian; Marvin, Jessica M. C.; Jones, Laura M.; Yusup, Hazijah B.; Lafond-Lapalme, Joël; Esquibet, Magali; Sabeh, Michael; Rott, Michael; Overmars, Hein; Finkers-Tomczak, Anna; Smant, Geert; Koutsovoulos, Georgios; Blok, Vivian; Mantelin, Sophie; Cock, Peter J. A.; Phillips, Wendy; Henrissat, Bernard; Urwin, Peter E.; Blaxter, Mark; Jones, John T. (2016-06-10) - Journal article
      Background. The yellow potato cyst nematode, Globodera rostochiensis, is a devastating plant pathogen of global economic importance. This biotrophic parasite secretes effectors from pharyngeal glands, some of which were ...
    • Genome sequence of a recently emerged, highly transmissible, multi-antibiotic- and antiseptic-resistant variant of methicillin-resistant Staphylococcus aureus, sequence type 239 (TW) 

      Holden, Matthew T. G.; Lindsay, Jodi A.; Corton, Craig; Quail, Michael A.; Cockfield, Joshua D.; Pathak, Smriti; Batra, Rahul; Parkhill, Julian; Bentley, Stephen D.; Edgeworth, Jonathan D. (2010-02) - Journal article
      The 3.1-Mb genome of an outbreak methicillin-resistant Staphylococcus aureus (MRSA) strain (TW20) contains evidence of recently acquired DNA, including two large regions ( 635 kb and 127 kb). The strain is resistant to a ...
    • The Phytophthora infestans haustorium is a site for secretion of diverse classes of infection-associated proteins 

      Wang, Shumei; Welsh, Lydia; Thorpe, Peter; Whisson, Stephen C; Boevink, Petra C; Birch, Paul R J (2018-08-28) - Journal article
      The oomycete potato blight pathogen Phytophthora infestans secretes a diverse set of proteins to manipulate host plant immunity. However, there is limited knowledge about how and where they are secreted during infection. ...
    • Plasmodium knowlesi – an emerging pathogen 

      Ahmed, M.A.; Cox Singh, Janet (2015-04) - Journal item
      Ten years have passed since the publication of a large focus of Plasmodium knowlesi infections in the human population. The discovery was made during molecular investigation of atypical P. malariae cases in the Kapit Health ...
    • Resource supply and the evolution of public-goods cooperation in bacteria 

      Brockhurst, Michael A.; Buckling, Angus; Racey, Dan; Gardner, Andy (2008-05-14) - Journal article
      Background: Explaining public-goods cooperation is a challenge for evolutionary biology. However, cooperation is expected to more readily evolve if it imposes a smaller cost. Such costs of cooperation are expected to decline ...
    • Spite and the scale of competition in Pseudomonas aeruginosa 

      Inglis, R. Fredrik; Roberts, Patrick Garfjeld; Gardner, Andy; Buckling, Angus (2011-08) - Journal article
      Scale of competition has been shown to be an important factor in shaping the evolution of social interactions. Although many theoretical and experimental studies have examined its effect on altruistic cooperation, relatively ...
    • Studies on influenza A virus PB1-F2 protein 

      Vater, Sandra (University of St Andrews, 2011-11-30) - Thesis
      The influenza A virus genome codes for up to 12 proteins. Segment 2 encodes three proteins, the polymerase subunit PB1, a small protein PB1-F2 and an N-terminally truncated version of PB1 called N40. Different functions ...
    • Whole genome sequencing identifies zoonotic transmission of MRSA isolates with the novel mecA homologue mecC 

      Harrison, Ewan M.; Paterson, Gavin K.; Holden, Matthew Thomas Geoffrey; Larsen, Jesper; Stegger, Marc; Larsen, Anders Rhod; Petersen, Andreas; Skov, Robert L.; Christensen, Judit Marta; Zeuthen, Anne Bak; Heltberg, Ole; Harris, Simon R.; Zadoks, Ruth N.; Parkhill, Julian; Peacock, Sharon J.; Holmes, Mark A. (2013-04) - Journal article
      Several methicillin-resistant Staphylococcus aureus (MRSA) lineages that carry a novel mecA homologue (mecC) have recently been described in livestock and humans. In Denmark, two independent human cases of mecC-MRSA infection ...