Now showing items 1-6 of 6

    • Applications of microfluidic chips in optical manipulation & photoporation 

      Marchington, Robert F. (University of St Andrews, 2010-10-01) - Thesis
      Integration and miniaturisation in electronics has undoubtedly revolutionised the modern world. In biotechnology, emerging lab-on-a-chip (LOC) methodologies promise all-integrated laboratory processes, to perform complete ...
    • Applications of microfluidics and optical manipulation for photoporation and imaging 

      Rendall, Helen A. (University of St Andrews, 2015-06-24) - Thesis
      Optical manipulation covers a wide range of techniques to guide and trap cells using only the forces exerted by light. Another optical tool is photoporation, the technique of injecting membrane-impermeable molecules using ...
    • Femtosecond optoinjection of intact tobacco BY-2 cells using a reconfigurable photoporation platform 

      Mitchell, C.A.; Kalies, S.; Cizmár, T.; Heisterkamp, A.; Torrance, L.; Roberts, A.G.; Gunn-Moore, F.J.; Dholakia, K. (2013-11-14) - Journal article
      A tightly-focused ultrashort pulsed laser beam incident upon a cell membrane has previously been shown to transiently increase cell membrane permeability while maintaining the viability of the cell, a technique known as ...
    • Photoporation and optical manipulation of plant and mammalian cells 

      Mitchell, Claire A. (University of St Andrews, 2015-06-24) - Thesis
      Optical cell manipulation allows precise and non-invasive exploration of mammalian cell function and physiology for medical applications. Plants, however, represent a vital component of the Earth’s ecosystem and the knowledge ...
    • Tailoring optical fibers for cell transfection 

      Ma, Nan (University of St Andrews, 2012-11-30) - Thesis
      Optical transfection is a promising technique for the delivery of foreign genetic material into cells by transiently changing the permeability of the cell membrane. Of the different optical light sources that have been ...
    • Ultrashort laser pulse shaping for novel light fields and experimental biophysics 

      Rudhall, Andrew Peter (University of St Andrews, 2013-06-26) - Thesis
      Broadband spectral content is required to support ultrashort pulses. However this broadband content is subject to dispersion and hence the pulse duration of corresponding ultrashort pulses may be stretched accordingly. I ...